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6/28/2018 10:44:41 AM | Browse: 184 | Download: 108
Publication Name World Journal of Psychiatry
Manuscript ID 38857
Country of Manuscript Source Australia
Received
2018-03-19 12:17
Peer-Review Started
2018-03-19 12:43
To Make the First Decision
2018-05-09 00:28
Return for Revision
2018-05-09 02:51
Revised
2018-05-15 04:36
Second Decision
2018-06-07 10:15
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-06-09 02:05
Articles in Press
2018-06-09 02:05
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2018-06-24 11:10
Publish the Manuscript Online
2018-06-28 10:44
ISSN 2220-3206 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Psychiatry
Manuscript type Review
Article Title Glutamate transporters, EAAT1 and EAAT2, are potentially important in the pathophysiology and treatment of schizophrenia and affective disorders
Manuscript Source Invited Manuscript
All Author List Georgia M Parkin, Madhara Udawela, Andrew Gibbons and Brian Dean
ORCID
Author(s) ORCID Number
Georgia M Parkin http://orcid.org/0000-0002-0588-2239
Madhara Udawela http://orcid.org/0000-0001-6258-0408
Andrew Gibbons http://orcid.org/0000-0001-7395-3660
Brian Dean http://orcid.org/0000-0001-7773-4473
Funding Agency and Grant Number
Corresponding author Georgia M Parkin, BSc, MSc, Molecular Psychiatry Laboratory, the Florey Institute of Neuroscience and Mental Health, 30 Royal Parade, Parkville 3052, VIC, Australia. georgia.parkin@florey.edu.au
Keywords Glia; Excitatory amino acid transporter; Psychiatry; Affective disorders; Glutamate transporter; Glutamate; Schizophrenia
Core Tip Following release from the presynaptic neuron, the majority of glutamate within the human cortex is taken up into glia cells where it is converted into glu­tamine for recycling back into glutamate. Glutamate transporters excitatory amino acid transporter (EAAT) 1 and EAAT2 are predominantly localized in the glial pl­asma membrane, and are responsible for the majority of glutamate uptake within the human brain. Here we provide a comprehensive review of the unique re­gula­tion of EAAT1 and EAAT2 mRNA and protein in health and psychiatric disorder, and in response to medication use.
Publish Date 2018-06-28 10:44
Citation Parkin GM, Udawela M, Gibbons A, Dean B. Glutamate transporters, EAAT1 and EAAT2, are potentially important in the pathophysiology and treatment of schizophrenia and affective disorders. World J Psychiatr 2018; 8(2): 51-63
Url http://www.wjgnet.com/2220-3206/full/v8/i2/51.htm
DOI http://dx.doi.org/10.5498/wjp.v8.i2.51
Full Article (PDF) WJP-8-51.pdf
Full Article (Word) WJP-8-51.doc
Manuscript File 38857-Review.docx
Answering Reviewers 38857-Answering reviewers.pdf
Audio Core Tip 38857-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 38857-Conflict-of-interest statement.pdf
Copyright License Agreement 38857-Copyright license agreement.pdf
Peer-review Report 38857-Peer-review(s).pdf
Scientific Misconduct Check 38857-Scientific misconduct check.pdf
Scientific Editor Work List 38857-Scientific editor work list.pdf