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Articles Published Processes
8/27/2018 10:18:26 AM | Browse: 1213 | Download: 1663
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Received |
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2018-03-29 23:42 |
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Peer-Review Started |
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2018-03-30 07:40 |
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To Make the First Decision |
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2018-04-23 05:41 |
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Return for Revision |
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2018-04-25 06:12 |
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Revised |
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2018-07-11 19:13 |
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Second Decision |
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2018-07-13 08:56 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2018-07-16 05:35 |
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Articles in Press |
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2018-07-16 05:35 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2018-08-27 07:59 |
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Publish the Manuscript Online |
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2018-08-27 10:18 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Review |
| Article Title |
Stem cell-derived exosomes - an emerging tool for myocardial regeneration
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Erzsebet Lazar, Theodora Benedek, Szilamer Korodi, Nora Rat, Jocelyn Lo and Imre Benedek |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Romanian Ministry of European Funds, the Romanian Government and the European Union |
103544/2016 - PLaqueIMAGE |
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| Corresponding Author |
Theodora Benedek, MD, PhD, Full Professor, Department of Internal Medicine, Clinic of Cardiology, University of Medicine and Pharmacy Tirgu Mures, Gheorghe Marinescu Street No. 38, Tirgu Mures 540136, Romania. theodora.benedek@gmail.com |
| Key Words |
Acute myocardial infarction; Exosome; Stem cell; Cardiac regeneration; Cardiovascular diseases |
| Core Tip |
Regenerative therapy represents the ultimate goal for restoring the function of damaged myocardium by stimulating the regeneration of infarcted tissue. Exosomes are small microvesicles released by living cells that act as miRNA nanocarriers, and exosomes can stimulate and modulate cellular proliferation and regeneration. Elevated exosome levels have been detected in human plasma in various cardiovascular diseases. Furthermore, myocardium-derived exosomes are potentially associated with myocardial healing. Given their paracrine properties, myocardium-derived exosomes have been proposed as a potential therapeutic option for myocardial regeneration. This review discusses the emerging roles of exosomes as candidate biomarkers and innovative therapies for cardiac regeneration. |
| Publish Date |
2018-08-27 10:18 |
| Citation |
Lazar E, Benedek T, Korodi S, Rat N, Lo J, Benedek I. Stem cell-derived exosomes - an emerging tool for myocardial regeneration. World J Stem Cells 2018; 10(8): 106-115 |
| URL |
http://www.wjgnet.com/1948-0210/full/v10/i8/106.htm |
| DOI |
http://dx.doi.org/10.4252/wjsc.v10.i8.106 |
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