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9/15/2018 11:10:20 AM | Browse: 374 | Download: 281
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 39281
Country/Territory India
Received
2018-04-16 02:03
Peer-Review Started
2018-04-16 11:50
To Make the First Decision
2018-05-02 03:41
Return for Revision
2018-05-03 06:15
Revised
2018-06-05 14:57
Second Decision
2018-06-27 08:30
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-06-28 16:25
Articles in Press
2018-06-28 16:25
Publication Fee Transferred
Edit the Manuscript by Language Editor
2018-07-09 16:27
Typeset the Manuscript
2018-09-14 01:13
Publish the Manuscript Online
2018-09-15 11:10
ISSN 1948-5204 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Review
Article Title Colorectal carcinogenesis: Insights into the cell death and signal transduction pathways: A review
Manuscript Source Invited Manuscript
All Author List Ashok Kumar Pandurangan, Thomas Divya, Kalaivani Kumar, Vadivel Dineshbabu, Bakthavatchalam Velavan and Ganapasam Sudhandiran
ORCID
Author(s) ORCID Number
Ashok Kumar Pandurangan http://orcid.org/0000-0003-2824-1757
Thomas Divya http://orcid.org/0000-0003-1098-7876
Kalaivani Kumar http://orcid.org/0000-0003-4150-6529
Vadivel Dineshbabu http://orcid.org/0000-0001-9923-7291
Bakthavatchalam Velavan http://orcid.org/0000-0002-1587-9236
Ganapasam Sudhandiran http://orcid.org/0000-0003-0066-7801
Funding Agency and Grant Number
Corresponding author Ganapasam Sudhandiran, MPhil, MSc, PhD, Associate Professor, Cell Biology Laboratory, Department of Biochemistry, University of Madras, Guindy Campus, Chennai 600025, India. sudhandiran@yahoo.com
Key Words Colorectal cancer; Cell death; Apoptosis; Autophagy; Inflammation; Hippo signalling; Nuclear factor erythroid 2-related factor 2; Wnt signaling
Core Tip Colorectal carcinogenesis (CRC) imposes a major health burden. This review addresses the cell death mechanisms and major signal transduction pathways involved in CRC. Regulated cell death is im­portant for maintaining normal homeostasis, and the dysregulation of cell death processes leads to a spectrum of diseases including cancer. It is interesting to note that cell death pathways collaborate with each other, so understanding the various cell death mechanisms are therefore essential. CRC is orchestrated by various signal transduction pathways, which are used as drug targets. This review highlights the key concepts concerning cell death mechanisms and signal transduction in CRC.
Publish Date 2018-09-15 11:10
Citation Pandurangan AK, Divya T, Kumar K, Dineshbabu V, Velavan B, Sudhandiran G. Colorectal carcinogenesis: Insights into the cell death and signal transduction pathways: A review. World J Gastrointest Oncol 2018; 10(9): 244-259
Url http://www.wjgnet.com/1948-5204/full/v10/i9/244.htm
DOI http://dx.doi.org/10.4251/wjgo.v10.i9.244
Full Article (PDF) WJGO-10-244.pdf
Full Article (Word) WJGO-10-244.doc
Manuscript File 39281-Review.docx
Answering Reviewers 39281-Answering reviewers.pdf
Audio Core Tip 39281-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 39281-Conflict-of-interest statement.pdf
Copyright License Agreement 39281-Copyright license agreement.pdf
Peer-review Report 39281-Peer-review(s).pdf
Scientific Misconduct Check 39281-Scientific misconduct check.pdf
Scientific Editor Work List 39281-Scientific editor work list.pdf