Publication Name	World Journal of Gastroenterology
Manuscript ID	39311
Country	Italy

Received	2018-04-20 01:13
Peer-Review Started	2018-04-21 12:06
First Decision by Editorial Office Director	2018-05-09 00:48
Return for Revision	2018-05-12 09:57
Revised	2018-05-18 10:25
Publication Fee Transferred
Second Decision by Editor	2018-06-08 09:03
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2018-06-12 03:19
Articles in Press	2018-06-12 03:19
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-06-25 07:06
Publish the Manuscript Online	2018-06-26 00:26

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Direct-acting antivirals and hepatocellular carcinoma in chronic hepatitis C: A few lights and many shadows
Manuscript Source	Invited Manuscript
All Author List	Maria Guarino, Anna Sessa, Valentina Cossiga, Federica Morando, Nicola Caporaso and Filomena Morisco
ORCID	Author(s) ORCID Number Maria Guarino http://orcid.org/0000-0002-0460-4122 Anna Sessa http://orcid.org/0000-0001-5168-6135 Valentina Cossiga http://orcid.org/0000- 0002-0000-1076 Federica Morando http://orcid.org/0000-0001-7044-8917 Nicola Caporaso http://orcid.org/0000-0001-8219-6489 Filomena Morisco http://orcid.org/0000-0002-9059-8311
Funding Agency and Grant Number
Corresponding Author	Nicola Caporaso, MD, Full Professor, Gastroenterology Unit, Department of Clinical Medicine and Surgery, University of Naples Federico II, via S. Pansini 5, Naples 80131, Italy. nicola.caporaso@unina.it
Key Words	Hepatocellular carcinoma; Hepatitis C virus; Direct-acting antiviral agents; Occurrence; Recurrence
Core Tip	A significant debate about the impact of direct-acting antiviral agents (DAAs) on the development of hepatocellular carcinoma (HCC) is currently ongoing. After a full review of the published literature, the evi­dence does not suggest that there is a higher rate of de novo HCC occurrence or recurrence after DAA therapy in patients with previous hepatitis C virus infection.
Publish Date	2018-06-26 00:26
Citation	Guarino M, Sessa A, Cossiga V, Morando F, Caporaso N, Morisco F; on behalf of the Special Interest Group on “Hepatocellular carcinoma and new anti-HCV therapies” of the Italian Association for the Study of the Liver. Direct-acting antivirals and hepatocellular carcinoma in chronic hepatitis C: a few lights and many shadows. World J Gastroenterol 2018; 24(24): 2582-2595
URL	http://www.wjgnet.com/1007-9327/full/v24/i24/2582.htm
DOI	http://dx.doi.org/10.3748/wjg.v24.i24.2582

Full Article (PDF)	WJG-24-2582.pdf
Manuscript File	39311-Review.docx
Answering Reviewers	39311-Answering reviewers.pdf
Audio Core Tip	39311-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	39311-Conflict-of-interest statement.pdf
Copyright License Agreement	39311-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	39311-Language certificate.pdf
Peer-review Report	39311-Peer-review(s).pdf
Scientific Misconduct Check	39311-Scientific misconduct check.pdf
Scientific Editor Work List	39311-Scientific editor work list.pdf