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Articles Published Processes
7/5/2018 1:33:43 AM | Browse: 1033 | Download: 1268
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Received |
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2018-04-13 00:57 |
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Peer-Review Started |
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2018-04-13 06:22 |
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To Make the First Decision |
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2018-04-27 01:59 |
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Return for Revision |
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2018-04-27 07:27 |
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Revised |
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2018-04-30 18:36 |
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Second Decision |
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2018-06-01 09:30 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2018-06-01 18:25 |
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Articles in Press |
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2018-06-01 18:25 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2018-07-03 03:48 |
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Publish the Manuscript Online |
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2018-07-05 01:33 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Meta-Analysis |
| Article Title |
Systematic review and meta-analysis on the association of tuberculosis in Crohn’s disease patients treated with tumor necrosis factor-α inhibitors (Anti-TNFα)
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Brent L Cao, Ahmad Qasem, Robert C Sharp, Latifa S Abdelli and Saleh A Naser |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Saleh A Naser, PhD, Academic Research, Full Professor, Instructor, Lecturer, Professor, Teacher, Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, 4110 Libra Drive, Orlando, FL 32816, United States. saleh.naser@ucf.edu |
| Key Words |
Tuberculosis; Tumor necrosis factor-alpha inhibitors; Crohn’s Disease; Meta-analysis; Systematic review |
| Core Tip |
The increased risk of Mycobacterium tuberculosis (TB) and other Mycobacterium species when on tumor necrosis factor-alpha (TNFα) inhibitor treatments has been a problem in patients with autoimmune disorders, such as Crohn’s disease (CD). This meta-analysis examines in detail the clinical trials that involve CD patients on TNFα inhibitors and their risk of developing TB infections. Our data concludes that, out of twenty-three studies examined, TNFα inhibitors are indeed associated with an increased risk of TB infection in CD patients. Knowledge of this data could help re-analyze what medications autoimmune patients should be prescribed to and evaluate possible linkages to Mycobacterium avium subspecies paratuberculosis infection. Thus, this information should be used to further inform clinical decision making and research. |
| Publish Date |
2018-07-05 01:33 |
| Citation |
Cao BL, Qasem A, Sharp RC, Abdelli LS, Naser SA. Systematic review and meta-analysis on the association of tuberculosis in Crohn’s disease patients treated with tumor necrosis factor-α inhibitors (Anti-TNFα). World J Gastroenterol 2018; 24(25): 2764-2775 |
| URL |
http://www.wjgnet.com/1007-9327/full/v24/i25/2764.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v24.i25.2764 |
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