Publication Name	World Journal of Clinical Oncology
Manuscript ID	39596
Country	Brazil

Received	2018-04-30 07:30
Peer-Review Started	2018-04-30 11:29
To Make the First Decision	2018-05-18 01:06
Return for Revision	2018-05-18 08:57
Revised	2018-06-23 23:15
Second Decision	2018-06-26 11:36
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2018-06-28 02:49
Articles in Press	2018-06-28 02:49
Publication Fee Transferred
Edit the Manuscript by Language Editor	2018-07-05 19:16
Typeset the Manuscript	2018-09-11 11:17
Publish the Manuscript Online	2018-09-14 11:38

ISSN	2218-4333 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Review
Article Title	Role of polymorphisms in genes that encode cytokines and Helicobacter pylori virulence factors in gastric carcinogenesis
Manuscript Source	Invited Manuscript
All Author List	Breno Bittencourt de Brito, Filipe Antônio França da Silva and Fabrício Freire de Melo
ORCID	Author(s) ORCID Number Breno Bittencourt de Brito http://orcid.org/0000-0002-1831-7909 Filipe Antônio França da Silva http://orcid.org/0000-0002-0550-1109 Fabrício Freire de Melo http://orcid.org/0000-0002-5680-2753
Funding Agency and Grant Number
Corresponding Author	Fabrício Freire de Melo, PhD, Professor, Instituto Multidisciplinar em Saúde, Universidade Federal da Bahia, Rua Hormindo Barros, 58, Quadra 17, Lote 58, Vitória da Conquista 45029-094, Brazil. freiremelo@yahoo.com.br
Key Words	Helicobacter pylori; Virulence factors; Cytokines; Gene polymorphisms; Gastric cancer
Core Tip	Various polymorphisms in host genes that encode cytokines and Helicobacter pylori virulence factors have been associated with different tendencies of gastric diseases development. Several reviews have been written on the role of host and bacterial isolated factors in gastric carcinogenesis. However, only a small amount of reviews unites the important characteristics of both bacterium and host in carcinogenesis. General overviews about polymorphisms in genes that enco­de cytokines are also scarce. We aimed to join the main polymorphisms in genes that encode cytokines and bacterial virulent factors related to gastric car­cinogenesis and to provide a broad overview about these themes.
Publish Date	2018-09-14 11:38
Citation	de Brito BB, da Silva FAF, de Melo FF. Role of polymorphisms in genes that encode cytokines and Helicobacter pylori virulence factors in gastric carcinogenesis. World J Clin Oncol 2018; 9(5): 83-89
URL	http://www.wjgnet.com/2218-4333/full/v9/i5/83.htm
DOI	http://dx.doi.org/10.5306/wjco.v9.i5.83

Full Article (PDF)	WJCO-9-83.pdf
Full Article (Word)	WJCO-9-83.doc
Manuscript File	39596-Review.docx
Answering Reviewers	39596-Answering reviewers.pdf
Audio Core Tip	39596-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	39596-Conflict-of-interest statement.pdf
Copyright License Agreement	39596-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	39596-Language certificate.pdf
Peer-review Report	39596-Peer-review(s).pdf
Scientific Misconduct Check	39596-Scientific misconduct check.pdf
Scientific Editor Work List	39596-Scientific editor work list.pdf