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10/26/2018 2:57:35 PM | Browse: 822 | Download: 1121
Publication Name World Journal of Clinical Cases
Manuscript ID 39617
Country United Kingdom
Received
2018-05-05 07:42
Peer-Review Started
2018-05-05 08:47
To Make the First Decision
2018-07-09 07:50
Return for Revision
2018-07-10 07:50
Revised
2018-09-08 17:32
Second Decision
2018-09-12 10:16
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-10-09 17:10
Articles in Press
2018-10-09 17:10
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2018-10-19 02:38
Publish the Manuscript Online
2018-10-26 14:57
ISSN 2307-8960 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, Research & Experimental
Manuscript Type Case Report
Article Title Gemcitabine-induced haemolytic uremic syndrome, although infrequent, can it be prevented: A case report and review of literature
Manuscript Source Invited Manuscript
All Author List Esther U Cidon, Pilar A Martinez and Tamas Hickish
ORCID
Author(s) ORCID Number
Esther U Cidon http://orcid.org/0000-0002-8650-5821
Pilar A Martinez http://orcid.org/0000-0002-5593-7402
Tamas Hickish http://orcid.org/0000-0001-6770-7279
Funding Agency and Grant Number
Corresponding Author Esther U Cidon, MD, MSc, PhD, Doctor, Department of Medical Oncology, Royal Bournemouth and Christchurch Hospital NHS Foundation Trust, Castle Lane East, Bournemouth BH7 7DW, United Kingdom. esther.unacidon@rbch.nhs.uk
Key Words Thrombocytopenia; Haemolytic uremic syndrome; Thrombotic microangiopathy; Gemcitabine; Microangiopathic haemolytic anaemia
Core Tip Gemcitabine has a well-known toxicity pro­file though rare cases of acute renal failure caused by haemolytic uremic syndrome (HUS) have also been reported. The cause of HUS remains unknown but its consequences may be lethal. HUS consists of progre­ssive renal failure with microangiopathic haemolytic anaemia and thrombocytopenia. Thrombotic microan­giopathy is the histopathological lesion and this affects mainly renal microvasculature. We present a case of gemcitabine-induced HUS and review literature to ma­ke professionals fully aware of its existence, thus a high grade of suspicion might help with early diagnosis and prompt treatment which hopefully will reduce its morbidity.
Publish Date 2018-10-26 14:57
Citation Cidon EU, Martinez PA, Hickish T. Gemcitabine-induced haemolytic uremic syndrome, although infrequent, can it be prevented: A case report and review of literature. World J Clin Cases 2018; 6(12): 531-537
URL http://www.wjgnet.com/2307-8960/full/v6/i12/531.htm
DOI http://dx.doi.org/10.12998/wjcc.v6.i12.531
Full Article (PDF) WJCC-6-531.pdf
Full Article (Word) WJCC-6-531.doc
CARE Checklist–2016 39617-CARE checklist (2013).pdf
Manuscript File 39617-Review.docx
Answering Reviewers 39617-Answering reviewers.pdf
Audio Core Tip 39617-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 39617-Conflict-of-interest statement.pdf
Copyright License Agreement 39617-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 39617-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate 39617-Non-Native Speakers of English Editing Certificate.docx
Supplementary Material 39617-Supplementary-Material-revision.docx
Peer-review Report 39617-Peer-review(s).pdf
Scientific Misconduct Check 39617-Scientific misconduct check.pdf
Scientific Editor Work List 39617-Scientific editor work list.pdf