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Articles Published Processes
10/26/2018 2:57:35 PM | Browse: 963 | Download: 1505
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Received |
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2018-05-05 07:42 |
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Peer-Review Started |
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2018-05-05 08:47 |
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To Make the First Decision |
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2018-07-09 07:50 |
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Return for Revision |
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2018-07-10 07:50 |
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Revised |
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2018-09-08 17:32 |
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Second Decision |
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2018-09-12 10:16 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2018-10-09 17:10 |
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Articles in Press |
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2018-10-09 17:10 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2018-10-19 02:38 |
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Publish the Manuscript Online |
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2018-10-26 14:57 |
ISSN |
2307-8960 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Medicine, Research & Experimental |
Manuscript Type |
Case Report |
Article Title |
Gemcitabine-induced haemolytic uremic syndrome, although infrequent, can it be prevented: A case report and review of literature
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Manuscript Source |
Invited Manuscript |
All Author List |
Esther U Cidon, Pilar A Martinez and Tamas Hickish |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Esther U Cidon, MD, MSc, PhD, Doctor, Doctor, Department of Medical Oncology, Royal Bournemouth and Christchurch Hospital NHS Foundation Trust, Castle Lane East, Bournemouth BH7 7DW, United Kingdom. esther.unacidon@rbch.nhs.uk |
Key Words |
Thrombocytopenia; Haemolytic uremic syndrome; Thrombotic microangiopathy; Gemcitabine; Microangiopathic haemolytic anaemia |
Core Tip |
Gemcitabine has a well-known toxicity profile though rare cases of acute renal failure caused by haemolytic uremic syndrome (HUS) have also been reported. The cause of HUS remains unknown but its consequences may be lethal. HUS consists of progressive renal failure with microangiopathic haemolytic anaemia and thrombocytopenia. Thrombotic microangiopathy is the histopathological lesion and this affects mainly renal microvasculature. We present a case of gemcitabine-induced HUS and review literature to make professionals fully aware of its existence, thus a high grade of suspicion might help with early diagnosis and prompt treatment which hopefully will reduce its morbidity. |
Publish Date |
2018-10-26 14:57 |
Citation |
Cidon EU, Martinez PA, Hickish T. Gemcitabine-induced haemolytic uremic syndrome, although infrequent, can it be prevented: A case report and review of literature. World J Clin Cases 2018; 6(12): 531-537 |
URL |
http://www.wjgnet.com/2307-8960/full/v6/i12/531.htm |
DOI |
http://dx.doi.org/10.12998/wjcc.v6.i12.531 |
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