Publication Name	World Journal of Gastroenterology
Manuscript ID	39870
Country	Japan

Received	2018-05-18 02:27
Peer-Review Started	2018-05-18 07:40
To Make the First Decision	2018-05-30 01:15
Return for Revision	2018-06-04 08:47
Revised	2018-06-07 00:01
Second Decision	2018-06-21 09:11
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2018-06-21 17:49
Articles in Press	2018-06-21 17:49
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-07-25 03:17
Publish the Manuscript Online	2018-07-27 06:43

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Letter to the Editor
Article Title	Genetic analysis is helpful for the diagnosis of small bowel ulceration
Manuscript Source	Unsolicited Manuscript
All Author List	Junji Umeno, Takayuki Matsumoto, Atsushi Hirano, Yuta Fuyuno and Motohiro Esaki
ORCID	Author(s) ORCID Number Junji Umeno http://orcid.org/0000-0002-5253-5600 Takayuki Matsumoto http://orcid.org/0000-0001-9786-3854 Atsushi Hirano http://orcid.org/0000-0002-4791-4550 Yuta Fuyuno http://orcid.org/0000-0003-3527-5648 Motohiro Esaki http://orcid.org/0000-0002-1195-0074
Funding Agency and Grant Number	Funding Agency Grant Number Practical Research Project for Rare/Intractable Diseases from Japan Agency for Medical Research and Development (AMED) 15ek0109053h0002 Japan Society for the Promotion of Science (JSPS) KAKENHI 25460953
Corresponding Author	Junji Umeno, MD, PhD, Doctor, Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, higashi-ku, Fukuoka 812-8582, Fukuoka, Japan. jumeno@intmed2.med.kyushu-u.ac.jp
Key Words	Cryptogenic multifocal ulcerous stenosing enteritis; Chronic nonspecific multiple ulcers of the small intestine; Chronic enteropathy associated with SLCO2A1 gene; Crohn’s disease
Core Tip	The purpose of this letter to the editor is to comment on the differential diagnosis of small intestinal ulcers. Mutations in PLA2G4A and SLCO2A1, encoding proteins involved in the production and degradation of prostaglandins, cause rare gastrointestinal diseases with multiple small intestinal ulcers. In addition to conventional gastrointestinal examinations, genetic analyses are helpful in distinguishing these diseases.
Publish Date	2018-07-27 06:43
Citation	Umeno J, Matsumoto T, Hirano A, Fuyuno Y, Esaki M. Genetic analysis is helpful for the diagnosis of small bowel ulceration. World J Gastroenterol 2018; 24(28): 3198-3200
URL	http://www.wjgnet.com/1007-9327/full/v24/i28/3198.htm
DOI	http://dx.doi.org/10.3748/wjg.v24.i28.3198

Full Article (PDF)	WJG-24-3198.pdf
Manuscript File	39870-Review.docx
Answering Reviewers	39870-Answering reviewers.pdf
Audio Core Tip	39870-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	39870-Conflict-of-interest statement.pdf
Copyright License Agreement	39870-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	39870-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	39870-Language certificate.pdf
Peer-review Report	39870-Peer-review(s).pdf
Scientific Misconduct Check	39870-Scientific misconduct check.pdf
Scientific Editor Work List	39870-Scientific editor work list.pdf