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Articles Published Processes
9/4/2014 5:33:00 PM | Browse: 1277 | Download: 1347
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Received |
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2013-06-07 09:18 |
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Peer-Review Started |
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2013-06-07 17:59 |
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To Make the First Decision |
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2013-07-05 18:30 |
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Return for Revision |
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2013-07-17 18:14 |
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Revised |
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2013-09-12 23:48 |
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Second Decision |
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2013-11-04 18:01 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2013-11-05 10:14 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2013-11-19 11:14 |
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Typeset the Manuscript |
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2013-12-24 21:41 |
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Publish the Manuscript Online |
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2014-01-20 17:10 |
Category |
Oncology |
Manuscript Type |
Autobiography |
Article Title |
Apoptotic pathway induced by diallyl trisulfide in pancreatic cancer cells
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Manuscript Source |
Invited Manuscript |
All Author List |
Hong-Bing Ma, Shan Huang, Xiao-Ran Yin, Yang Zhang and Zheng-Li Di |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Science and Technology Program of Shaanxi Province |
2010K01-141 |
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Corresponding Author |
Hong-Bing Ma, PhD, Department of Radiotherapy of Tumor Hospital, the Second Hospital of Xian Jiaotong University, No. 157, Xiwulu, Xi’an 710004, Shaanxi Province, China. mhbxian@126.com |
Key Words |
Diallyl trisulfide; Apoptosis; Pancreatic cancer; Cell cycle; p53 |
Core Tip |
We investigated the effect of diallyl trisulfide (DATS), a promising cancer chemopreventive constituent of processed garlic, in human pancreatic cancer cells (Capan-2) and non-tumorigenic pancreatic ductal epithelial cells (H6C7), and explored the possible mechanism involved. We found that DATS can induce apoptosis in both cell lines. We also investigated the role of p53, Bcl-2 and the cell cycle in apoptosis of Capan-2 and H6C7 cells. |
Publish Date |
2014-01-20 17:10 |
Citation |
Ma HB, Huang S, Yin XR, Zhang Y, Di ZL. Apoptotic pathway induced by diallyl trisulfide in pancreatic cancer cells. World J Gastroenterol 2014; 20(1): 193-203 |
URL |
http://www.wjgnet.com/1007-9327/full/v20/i1/193.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v20.i1.193 |
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