Publication Name	World Journal of Clinical Cases
Manuscript ID	39993
Country	China

Received	2018-05-28 08:31
Peer-Review Started	2018-05-28 09:46
To Make the First Decision	2018-07-09 01:43
Return for Revision	2018-07-12 06:38
Revised	2018-07-27 08:55
Second Decision	2018-08-02 10:09
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2018-08-04 00:53
Articles in Press	2018-08-04 00:53
Publication Fee Transferred
Edit the Manuscript by Language Editor	2018-08-13 22:49
Typeset the Manuscript	2018-09-21 06:44
Publish the Manuscript Online	2018-09-26 09:00

ISSN	2307-8960 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Research progress on signaling pathways in cirrhotic portal hypertension
Manuscript Source	Unsolicited Manuscript
All Author List	Wen Xu and Yong-Ping Mu
ORCID	Author(s) ORCID Number Wen Xu http://orcid.org/0000-0003-2132-9537 Yong-Ping Mu http://orcid.org/0000-0002-4533-5563
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81573948
Corresponding Author	Yong-Ping Mu, PhD, Attending Doctor, Department of Gastroenterology and Hepatology, Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine (TCM), 528 Zhangheng Road, Pudong District, Shanghai 201203, China. ypmu8888@126.com
Key Words	PI3K-AKT-mTOR; Portal hypertension; Rho-associated kinases; Liver cirrhosis; Signaling pathways; Farnesoid X-activated receptors; JAK2/STAT3
Core Tip	Portal hypertension (PHT) is a syndrome of portal venous system hemodynamics in liver cirrhosis. Current therapeutic options are often insufficient to prevent progression of the disease. We therefore may find more effective clinical treatments by understanding the signal pathways involved in the disease. This paper is an up-to-date and thorough review of the signaling pathways that may be involved in the pathogenesis of PHT in liver cirrhosis.
Publish Date	2018-09-26 09:00
Citation	Xu W, Liu P, Mu YP. Research progress on signaling pathways in cirrhotic portal hypertension. World J Clin Cases 2018; 6(10): 335-343
URL	http://www.wjgnet.com/2307-8960/full/v6/i10/335.htm
DOI	http://dx.doi.org/10.12998/wjcc.v6.i10.335

Full Article (PDF)	WJCC-6-335.pdf
Full Article (Word)	WJCC-6-335.doc
Manuscript File	39993-Review.docx
Answering Reviewers	39993-Answering reviewers.pdf
Audio Core Tip	39993-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	39993-Conflict-of-interest statement.pdf
Copyright License Agreement	39993-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	39993-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	39993-Language certificate.pdf
Peer-review Report	39993-Peer-review(s).pdf
Scientific Misconduct Check	39993-Scientific misconduct check.pdf
Scientific Editor Work List	39993-Scientific editor work list.pdf