BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
9/25/2018 3:44:36 AM | Browse: 1048 | Download: 1635
 |
Received |
|
2018-05-30 01:42 |
|
Peer-Review Started |
|
2018-05-30 06:12 |
|
To Make the First Decision |
|
2018-07-04 01:14 |
|
Return for Revision |
|
2018-07-06 03:27 |
|
Revised |
|
2018-07-11 10:48 |
|
Second Decision |
|
2018-07-31 12:27 |
 |
Accepted by Journal Editor-in-Chief |
|
|
|
Accepted by Executive Editor-in-Chief |
|
2018-08-01 04:29 |
|
Articles in Press |
|
2018-08-01 04:29 |
|
Publication Fee Transferred |
|
|
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2018-09-20 07:59 |
|
Publish the Manuscript Online |
|
2018-09-25 03:44 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Physiology |
| Manuscript Type |
Review |
| Article Title |
Calcium-sensing receptor in colorectal inflammation and cancer: Current insights and future perspectives
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Luca Iamartino, Taha Elajnaf, Enikö Kallay and Martin Schepelmann |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| EU Horizon 2020 Research and Innovation |
675228 |
| Austrian Science Fund (FWF) |
P 29948-B28 |
|
| Corresponding Author |
Martin Schepelmann, PhD, Postdoctoral Fellow, Department of Pathophysiology and Allergy Research, Medical University of Vienna, Währinger Gürtel 18-20, Vienna 1090, Austria. martin.schepelmann@meduniwien.ac.at |
| Key Words |
Calcium-sensing receptor; Colon; Cancer; Inflammation; Calcimimetics; Calcilytics |
| Core Tip |
The extracellular calcium-sensing receptor (CaSR) is best known for its roles in maintaining body calcium homeostasis, but it is also expressed in the intestines where it is assumed to be involved in pathologies such as inflammatory bowel disease and colorectal cancer. It has been suggested to act as a tumour suppressor in colorectal tumourigenesis. In this review we highlight the evidence for the anti-inflammatory and anti-tumourigenic roles of the CaSR, its signalling pathways, and its potential for future use as a drug target in the context of inflammatory bowel disease and colorectal cancer. |
| Publish Date |
2018-09-25 03:44 |
| Citation |
Iamartino L, Elajnaf T, Kallay E, Schepelmann M. Calcium-sensing receptor in colorectal inflammation and cancer: Current insights and future perspectives. World J Gastroenterol 2018; 24(36): 4119-4131 |
| URL |
http://www.wjgnet.com/1007-9327/full/v24/i36/4119.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v24.i36.4119 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
