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Articles Published Processes
10/26/2018 11:38:21 AM | Browse: 930 | Download: 1666
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Received |
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2018-07-01 13:16 |
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Peer-Review Started |
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2018-07-02 11:37 |
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To Make the First Decision |
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2018-07-25 01:12 |
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Return for Revision |
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2018-07-25 03:26 |
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Revised |
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2018-08-16 13:51 |
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Second Decision |
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2018-09-04 08:06 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2018-10-05 23:25 |
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Articles in Press |
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2018-10-05 23:25 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2018-10-15 00:59 |
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Typeset the Manuscript |
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2018-10-22 07:28 |
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Publish the Manuscript Online |
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2018-10-26 11:38 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Outcomes of furazolidone- and amoxicillin-based quadruple therapy for Helicobacter pylori infection and predictors of failed eradication
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ya-Wen Zhang, Wei-Ling Hu, Yuan Cai, Wen-Fang Zheng, Qin Du, John J Kim, John Y Kao, Ning Dai and Jian-Min Si |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the Zhejiang Science and Technology Project |
LGF18H160012 |
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| Corresponding Author |
Wei-Ling Hu, MD, PhD, Doctor, Department of Gastroenterology, Sir Run Run Shaw Hospital, School of Medicine, Institute of Gastroenterology, Zhejiang University, No. 3 East Qingchun Road, Hangzhou 310016, Zhejiang Province, China. huweiling@zju.edu.cn |
| Key Words |
Helicobacter pylori; Furazolidone; Quadruple regimen; Side effects; Eradication |
| Core Tip |
This study examined the outcomes of furazolidone- and amoxicillin-based quadruple therapy as both primary and rescue therapies for Helicobacter pylori (H. pylori) infection in nearly a thousand patients. Detailed data on adverse events and factors associated with failed H. pylori eradication were evaluated. Furazolidone- and amoxicillin-based quadruple therapy demonstrated a high H. pylori eradication rate exceeding 90% with a favorable safety profile in a real-world setting. Abstinence from alcohol during therapy and strict medication adherence may further optimize eradication. The results validate updated guidelines recommending furazolidone-based quadruple therapy as a first-line treatment for H. pylori infection in areas with a high prevalence of clarithromycin resistance. |
| Publish Date |
2018-10-26 11:38 |
| Citation |
Zhang YW, Hu WL, Cai Y, Zheng WF, Du Q, Kim JJ, Kao YJ, Dai N, Si JM. Outcomes of furazolidone- and amoxicillin-based quadruple therapy for Helicobacter pylori infection and predictors of failed eradication. World J Gastroenterol 2018; 24(40): 4596-4605 |
| URL |
http://www.wjgnet.com/1007-9327/full/v24/i40/4596.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v24.i40.4596 |
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