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Articles Published Processes
10/18/2018 10:13:24 AM | Browse: 843 | Download: 1378
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Received |
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2018-06-29 07:27 |
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Peer-Review Started |
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2018-07-02 09:34 |
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To Make the First Decision |
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2018-07-12 02:23 |
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Return for Revision |
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2018-07-12 08:49 |
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Revised |
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2018-09-03 10:37 |
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Second Decision |
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2018-09-13 07:52 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2018-10-05 23:28 |
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Articles in Press |
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2018-10-05 23:28 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2018-10-10 01:11 |
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Typeset the Manuscript |
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2018-10-18 03:04 |
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Publish the Manuscript Online |
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2018-10-18 10:13 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Microbiology |
| Manuscript Type |
Observational Study |
| Article Title |
Fungal dysbiosis predicts the diagnosis of pediatric Crohn’s disease
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Mohammad I El Mouzan, Kirill S Korolev, Mohammad A Al Mofarreh, Rajita Menon, Harland S Winter, Ahmad A Al Sarkhy, Scot E Dowd, Ahmad M Al Barrag and Asaad A Assiri |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| The Deanship of Scientific Research, King Saud University, Saudi Arabia |
RGP-1436-007 |
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| Corresponding Author |
Mohammad I El Mouzan, MD, Professor, Department of Pediatrics, Gastroenterology Unit, College of Medicine, King Saud University, Riyadh 11461, Saudi Arabia. drmouzan@gmail.com |
| Key Words |
Fungiome; Mycobiome; Crohn’s disease; Inflammation; Saudi children |
| Core Tip |
We found high accuracy of fungal dysbiosis in predicting diagnosis of Crohn’s disease (CD), a finding similar to bacterial dysbiosis. However, the higher area under the curve for the fungal dysbiosis classifier in stool (0.85 ± 0.057) than in mucosa (0.71 ± 0.067) (P < 0.001), contrasts with bacterial studies, suggesting higher accuracy of stool samples. Although the clinical application of this finding is limited at present by the high cost of fungal analysis, such information is important from a scientific viewpoint, to increase the understanding of the role of fungal flora in CD and to stimulate further studies. |
| Publish Date |
2018-10-18 10:13 |
| Citation |
El Mouzan MI, Korolev KS, Al Mofarreh MA, Menon R, Winter HS, Al Sarkhy AA, Dowd SE, Al Barrag AM, Assiri AA. Fungal dysbiosis predicts the diagnosis of pediatric Crohn’s disease. World J Gastroenterol 2018; 24(39): 4510-4516 |
| URL |
http://www.wjgnet.com/1007-9327/full/v24/i39/4510.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v24.i39.4510 |
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