BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
10/18/2018 10:13:24 AM | Browse: 729 | Download: 986
Publication Name World Journal of Gastroenterology
Manuscript ID 40474
Country/Territory Saudi Arabia
Received
2018-06-29 07:27
Peer-Review Started
2018-07-02 09:34
To Make the First Decision
2018-07-12 02:23
Return for Revision
2018-07-12 08:49
Revised
2018-09-03 10:37
Second Decision
2018-09-13 07:52
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-10-05 23:28
Articles in Press
2018-10-05 23:28
Publication Fee Transferred
Edit the Manuscript by Language Editor
2018-10-10 01:11
Typeset the Manuscript
2018-10-18 03:04
Publish the Manuscript Online
2018-10-18 10:13
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Microbiology
Manuscript Type Observational Study
Article Title Fungal dysbiosis predicts the diagnosis of pediatric Crohn’s disease
Manuscript Source Unsolicited Manuscript
All Author List Mohammad I El Mouzan, Kirill S Korolev, Mohammad A Al Mofarreh, Rajita Menon, Harland S Winter, Ahmad A Al Sarkhy, Scot E Dowd, Ahmad M Al Barrag and Asaad A Assiri
ORCID
Author(s) ORCID Number
Mohammad I El Mouzan http://orcid.org/0000-0001-8699-3143
Kirill S Korolev http://orcid.org/0000-0003-1988-0645
Mohammad A Al Mofarreh http://orcid.org/0000-0001-5426-9425
Rajita Menon http://orcid.org/0000-0002-4767-0971
Harland S Winter http://orcid.org/0000-0003-1122-4811
Ahmad A Al Sarkhy http://orcid.org/0000-0002-1424-5784
Scot E Dowd http://orcid.org/0000-0002-6296-1427
Ahmad M Al Barrag http://orcid.org/0000-0002-8829-9371
Asaad A Assiri http://orcid.org/0000-0003-3357-5794
Funding Agency and Grant Number
Funding Agency Grant Number
The Deanship of Scientific Research, King Saud University, Saudi Arabia RGP-1436-007
Corresponding Author Mohammad I El Mouzan, MD, Professor, Department of Pediatrics, Gastroenterology Unit, College of Medicine, King Saud University, Riyadh 11461, Saudi Arabia. drmouzan@gmail.com
Key Words Fungiome; Mycobiome; Crohn’s disease; Inflammation; Saudi children
Core Tip We found high accuracy of fungal dysbiosis in predicting diagnosis of Crohn’s disease (CD), a finding similar to bacterial dysbiosis. However, the higher area under the curve for the fungal dysbiosis classifier in stool (0.85 ± 0.057) than in mucosa (0.71 ± 0.067) (P < 0.001), contrasts with bacterial studies, suggesting higher accuracy of stool samples. Although the clinical application of this finding is limited at present by the high cost of fungal analysis, such information is important from a scientific viewpoint, to increase the understanding of the role of fungal flora in CD and to stimulate further studies.
Publish Date 2018-10-18 10:13
Citation El Mouzan MI, Korolev KS, Al Mofarreh MA, Menon R, Winter HS, Al Sarkhy AA, Dowd SE, Al Barrag AM, Assiri AA. Fungal dysbiosis predicts the diagnosis of pediatric Crohn’s disease. World J Gastroenterol 2018; 24(39): 4510-4516
URL http://www.wjgnet.com/1007-9327/full/v24/i39/4510.htm
DOI http://dx.doi.org/10.3748/wjg.v24.i39.4510
Full Article (PDF) WJG-24-4510.pdf
Full Article (Word) WJG-24-4510.doc
STROBE Statement 40474-STROBE statement.pdf
Manuscript File 40474-Review.docx
Answering Reviewers 40474-Answering reviewers.pdf
Audio Core Tip 40474-Audio core tip.m4a
Biostatistics Review Certificate 40474-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 40474-Conflict-of-interest statement.pdf
Copyright License Agreement 40474-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 40474-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 40474-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 40474-Language certificate.pdf
Peer-review Report 40474-Peer-review(s).pdf
Scientific Misconduct Check 40474-Scientific misconduct check.pdf
Scientific Editor Work List 40474-Scientific editor work list.pdf