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Publication Name World Journal of Gastroenterology
Manuscript ID 4053
Country/Territory Brazil
Received
2013-06-11 22:03
Peer-Review Started
2013-06-12 19:04
To Make the First Decision
2013-07-05 18:38
Return for Revision
2013-07-18 11:30
Revised
2013-08-03 09:20
Second Decision
2013-08-19 12:29
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-08-20 00:26
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2013-10-14 18:20
Publish the Manuscript Online
2013-11-08 14:06
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Autobiography
Article Title No evidence of HPV DNA in esophageal squamous cell carcinoma in a population of Southern Brazil
Manuscript Source Invited Manuscript
All Author List Luís Carlos Moreira Antunes, João Carlos Prolla, Antonio de Barros Lopes, Marta Pires da Rocha and Renato Borges Fagundes
Funding Agency and Grant Number
Corresponding Author Renato Borges Fagundes, MD, PhD, Professor of Medicine, Programa de Pós-Graduação: Ciências em Gastroenterologia e Hepatologia - Universidade Federal do Rio Grande do Sul, Ramiro Barcelos, 2400 - 2° andar, Bairro Santana, Porto Alegre 90035-003, Rio Grande do Sul, Brasil. fagundesrb@gmail.com
Key Words Esophageal cancer; Esophageal squamous cell carcinoma; Human papillomavirus; Head and neck cancer; Polymerase chain reactions; Nested-polymerase chain reaction
Core Tip This paper gives additional evidence related to the controversy on the potential role of human papillomavirus (HPV) in the pathogenesis of esophageal squamous cell carcinoma (ESCC). Taking great care to avoid contamination by environmental HPV and using a very sensitive HPV DNA detection technique, we found no evidence of HPV neither in ESCC tumor tissue, nor in esophageal non-tumoral tissue from ESCC patients, or from head and neck squamous cell carcinoma patients or from dyspeptic controls without cancer. These data convincingly argue that when environmental contamination is carefully controlled, there is no evidence that HPV is involved in ESCC carcinogenesis in southern Brazil.
Publish Date 2013-11-08 14:06
Citation Antunes LCM, Prolla JC, de Barros Lopes A, da Rocha MP, Fagundes RB. No evidence of HPV DNA in esophageal squamous cell carcinoma in a population of Southern Brazil. World J Gastroenterol 2013; 19(39): 6598-6603
URL http://www.wjgnet.com/1007-9327/full/v19/i39/6598.htm
DOI http://dx.doi.org/10.3748/wjg.v19.i39.6598
Full Article (PDF) WJG-19-6598.pdf
Manuscript File 4053-Review.docx
Answering Reviewers 4053-Answering reviewers.pdf
Biostatistics Review Certificate Biostatistician Review Report.pdf
Copyright License Agreement 4053-Copyright assignment.doc
Institutional Review Board Approval Form or Document Scientific Committee and Research Ethical Comission.pdf
Non-Native Speakers of English Editing Certificate 4053-Language certificate.pdf
Peer-review Report 4053-Peer reviewer(s).pdf
Scientific Editor Work List 4053-Scientific editor work list.doc