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11/13/2018 8:04:45 AM | Browse: 921 | Download: 1212
Publication Name World Journal of Gastroenterology
Manuscript ID 40559
Country/Territory Spain
Received
2018-07-05 00:38
Peer-Review Started
2018-07-05 02:26
To Make the First Decision
2018-08-27 02:25
Return for Revision
2018-08-28 02:47
Revised
2018-09-27 13:07
Second Decision
2018-10-15 08:43
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-10-15 18:25
Articles in Press
2018-10-15 18:25
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2018-11-09 05:53
Publish the Manuscript Online
2018-11-13 08:04
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Minireviews
Article Title CXC family of chemokines as prognostic or predictive biomarkers and possible drug targets in colorectal cancer
Manuscript Source Invited Manuscript
All Author List Sara Cabrero-de las Heras and Eva Martinez-Balibrea
ORCID
Author(s) ORCID Number
Sara Cabrero-de las Heras http://orcid.org/0000-0002-9364-5371
Eva Martinez-Balibrea http://orcid.org/0000-0002-4501-7100
Funding Agency and Grant Number
Funding Agency Grant Number
ISCIII PI16/01800 and PIE16/00011
Corresponding Author Eva Martinez-Balibrea, PhD, Senior Scientist, Program against Cancer Resistance (ProCURE) Catalan institute of oncology, Germans Trias i Pujol health research institute (IGTP), Carretera de Can Ruti, camí de les escoles s/n, Badalona, Barcelona 08916, Catalunya, Spain. embalibrea@iconcologia.net
Key Words Biomarkers; Treatment; Chemotherapy; Oxaliplatin; Irinotecan; Immunotherapy; Colorectal cancer; CXC chemokines; Immune system; Bevacizumab
Core Tip The contribution of the immune system to the development and progression of cancer is now fully acknowledged. The specific action of the immune system depends on the type of immune cells that are recruited to the tumor sites. Chemokines from the CXC subfamily are released by tumor cells and cells within the tumor microenvironment, whereupon they attract cells with anti-tumor (e.g., CD4+ and CD8+ lymphocytes) or pro-tumor activity (e.g., myeloid-derived suppressor cells). Chemokines have been proposed as prognostic factors, as biomarkers of response to therapy and as drug targets. The present review addresses the most recent findings in the field.
Publish Date 2018-11-13 08:04
Citation Cabrero-de las Heras S, Martínez-Balibrea E. CXC family of chemokines as prognostic or predictive biomarkers and possible drug targets in colorectal cancer. World J Gastroenterol 2018; 24(42): 4738-4749
URL http://www.wjgnet.com/1007-9327/full/v24/i42/4738.htm
DOI http://dx.doi.org/10.3748/wjg.v24.i42.4738
Full Article (PDF) WJG-24-4738.pdf
Full Article (Word) WJG-24-4738.docx
Manuscript File 40559-Review.docx
Answering Reviewers 40559-Answering reviewers.pdf
Audio Core Tip 40559-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 40559-Conflict-of-interest statement.pdf
Copyright License Agreement 40559-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 40559-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 40559-Language certificate.pdf
Peer-review Report 40559-Peer-review(s).pdf
Scientific Misconduct Check 40559-Scientific misconduct check.pdf
Scientific Editor Work List 40559-Scientific editor work list.pdf