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11/13/2018 8:04:45 AM | Browse: 869 | Download: 1321
Publication Name World Journal of Gastroenterology
Manuscript ID 41240
Country China
Received
2018-08-07 08:23
Peer-Review Started
2018-08-08 00:44
To Make the First Decision
2018-08-27 01:42
Return for Revision
2018-08-27 08:56
Revised
2018-09-03 06:28
Second Decision
2018-09-13 09:00
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2018-10-05 23:02
Articles in Press
2018-10-05 23:02
Publication Fee Transferred
Edit the Manuscript by Language Editor
2018-10-11 18:44
Typeset the Manuscript
2018-10-31 08:15
Publish the Manuscript Online
2018-11-13 08:04
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access Open-Access: This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Ubiquitin-like modifier activating enzyme 2 promotes cell migration and invasion through Wnt/β-catenin signaling in gastric cancer
Manuscript Source Unsolicited Manuscript
All Author List Ji Li, Xun Sun, Ping He, Wan-Qi Liu, Ya-Bin Zou, Quan Wang and Xiang-Wei Meng
ORCID
Author(s) ORCID Number
Ji Li http://orcid.org/0000-0003-3339-1063
Xun Sun http://orcid.org/0000-0001-6516-9972
Ping He http://orcid.org/0000-0003-0536-1887
Wan-Qi Liu http://orcid.org/0000-0002-2173-7023
Ya-Bin Zou http://orcid.org/0000-0003-1420-3792
Quan Wang http://orcid.org/0000-0003-0990-5415
Xiang-Wei Meng http://orcid.org/0000-0002-8452-2433
Funding Agency and Grant Number
Funding Agency Grant Number
Science and Technology department of Jilin Province No. 20150204006YY
Corresponding Author Xiang-Wei Meng, MD, Chief Doctor, Professor, Gastroenterology, First Hospital of Jilin University, No. 71 Xinmin Street, Changchun 130021, Jilin Province, China. mxwmengxiangwei@163.com
Key Words Ubiquitin-like modifier activating enzyme 2; Gastric cancer; Epithelial-mesenchymal transition; Wnt/β-catenin signaling pathway
Core Tip This study elucidated the function and me­chanism of action of ubiquitin-like modifier activating enzyme 2 (Uba2) in gastric cancer (GC) progression. Uba2 was knocked-down or over-expressed to examine its effects on proliferation, migration and invasion of GC cells. The effects of Uba2 on the Wnt/β-catenin pathway was investigated by Western blotting and luciferase reporter assay. Uba2 affected GC cell invasion and migration by modulating the Wnt/β-catenin signaling pathway, as well as epithelial-mesenchymal transition. This study was intended to create a preclinical basis to establish Uba2 as a new molecular drug target for GC.
Publish Date 2018-11-13 08:04
Citation Li J, Sun X, He P, Liu WQ, Zou YB, Wang Q, Meng XW. Ubiquitin-like modifier activating enzyme 2 promotes cell migration and invasion through Wnt/β-catenin signaling in gastric cancer. World J Gastroenterol 2018; 24(42): 4773-4786
URL http://www.wjgnet.com/1007-9327/full/v24/i42/4773.htm
DOI http://dx.doi.org/10.3748/wjg.v24.i42.4773
Full Article (PDF) WJG-24-4773.pdf
Full Article (Word) WJG-24-4773.doc
The ARRIVE Guidelines 41240-The ARRIVE guidelines.pdf
Manuscript File 41240-Review.docx
Answering Reviewers 41240-Answering reviewers.pdf
Audio Core Tip 41240-Audio core tip.mp3
Biostatistics Review Certificate 41240-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 41240-Conflict-of-interest statement.pdf
Copyright License Agreement 41240-Copyright License Agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 41240-Grant application form(s).pdf
Institutional Review Board Approval Form or Document 41240-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 41240-Language certificate.pdf
Peer-review Report 41240-Peer-review(s).pdf
Scientific Misconduct Check 41240-Scientific misconduct check.pdf
Scientific Editor Work List 41240-Scientific editor work list.pdf