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Articles Published Processes
11/27/2018 1:56:41 PM | Browse: 764 | Download: 1003
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Received |
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2018-08-02 06:15 |
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Peer-Review Started |
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2018-08-03 00:17 |
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To Make the First Decision |
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2018-08-27 01:31 |
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Return for Revision |
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2018-09-03 00:37 |
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Revised |
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2018-09-05 06:41 |
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Second Decision |
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2018-09-12 10:41 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2018-10-10 13:24 |
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Articles in Press |
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2018-10-10 13:24 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2018-10-22 04:53 |
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Typeset the Manuscript |
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2018-11-22 01:46 |
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Publish the Manuscript Online |
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2018-11-27 13:56 |
ISSN |
1948-5182 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Editorial |
Article Title |
Exosomal microRNAs as a potential therapeutic strategy in hepatocellular carcinoma
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Manuscript Source |
Invited Manuscript |
All Author List |
Angélique Gougelet |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Angélique Gougelet, PhD, Research Scientist, Inserm, U1016, Institut Cochin, 24, rue du Faubourg Saint Jacques, Paris 75014, France. angelique.gougelet@inserm.fr |
Key Words |
MicroRNAs; Hepatocellular carcinoma; Targeted therapy; Exosomes |
Core Tip |
Despite the intensive research efforts to identify the molecular events responsible for the emergence of liver cancer, hepatocellular carcinoma (HCC) remains a major health problem worldwide. Thus, the identification of new therapeutic opportunities to counteract the challenging issues linked to HCC heterogeneity and resistance to conventional treatments is a short-term necessity. Over the last few decades, microRNAs have appeared as interesting therapeutic strategies with their pleiotropic inhibitory action, but the use of a delivery system is a requirement for miRNA mimic administration. Exosomes, which are small vesicles naturally produced by immune cells and aberrantly by cancer cells, have recently emerged as a promising vehicle. |
Publish Date |
2018-11-27 13:56 |
Citation |
Gougelet A. Exosomal microRNAs as a potential therapeutic strategy in hepatocellular carcinoma. World J Hepatol 2018; 10(11): 785-789 |
URL |
http://www.wjgnet.com/1948-5182/full/v10/i11/785.htm |
DOI |
http://dx.doi.org/10.4254/wjh.v10.i11.785 |
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