Publication Name	World Journal of Hepatology
Manuscript ID	41335
Country	France

Received	2018-08-02 06:15
Peer-Review Started	2018-08-03 00:17
To Make the First Decision	2018-08-27 01:31
Return for Revision	2018-09-03 00:37
Revised	2018-09-05 06:41
Second Decision	2018-09-12 10:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2018-10-10 13:24
Articles in Press	2018-10-10 13:24
Publication Fee Transferred
Edit the Manuscript by Language Editor	2018-10-22 04:53
Typeset the Manuscript	2018-11-22 01:46
Publish the Manuscript Online	2018-11-27 13:56

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Editorial
Article Title	Exosomal microRNAs as a potential therapeutic strategy in hepatocellular carcinoma
Manuscript Source	Invited Manuscript
All Author List	Angélique Gougelet
ORCID	Author(s) ORCID Number Angélique Gougelet http://orcid.org/0000-0001-7464-9804
Funding Agency and Grant Number
Corresponding Author	Angélique Gougelet, PhD, Research Scientist, Inserm, U1016, Institut Cochin, 24, rue du Faubourg Saint Jacques, Paris 75014, France. angelique.gougelet@inserm.fr
Key Words	MicroRNAs; Hepatocellular carcinoma; Targeted therapy; Exosomes
Core Tip	Despite the intensive research efforts to identify the molecular events responsible for the em­ergence of liver cancer, hepatocellular carcinoma (HCC) remains a major health problem worldwide. Thus, the identification of new therapeutic opportunities to counteract the challenging issues linked to HCC hete­rogeneity and resistance to conventional treatments is a short-term necessity. Over the last few decades, microRNAs have appeared as interesting therapeutic strategies with their pleiotropic inhibitory action, but the use of a delivery system is a requirement for miRNA mimic administration. Exosomes, which are small vesi­cles naturally produced by immune cells and aberrantly by cancer cells, have recently emerged as a promising vehicle.
Publish Date	2018-11-27 13:56
Citation	Gougelet A. Exosomal microRNAs as a potential therapeutic strategy in hepatocellular carcinoma. World J Hepatol 2018; 10(11): 785-789
URL	http://www.wjgnet.com/1948-5182/full/v10/i11/785.htm
DOI	http://dx.doi.org/10.4254/wjh.v10.i11.785

Full Article (PDF)	WJH-10-785.pdf
Full Article (Word)	WJH-10-785.doc
Manuscript File	41335-Review.docx
Answering Reviewers	41335-Answering reviewers.pdf
Audio Core Tip	41335-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	41335-Conflict-of-interest statement.pdf
Copyright License Agreement	41335-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	41335-Language certificate.pdf
Peer-review Report	41335-Peer-review(s).pdf
Scientific Misconduct Check	41335-Scientific misconduct check.pdf
Scientific Editor Work List	41335-Scientific editor work list.pdf