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11/27/2018 1:56:41 PM | Browse: 764 | Download: 1003
Publication Name World Journal of Hepatology
Manuscript ID 41335
Country/Territory France
Received
2018-08-02 06:15
Peer-Review Started
2018-08-03 00:17
To Make the First Decision
2018-08-27 01:31
Return for Revision
2018-09-03 00:37
Revised
2018-09-05 06:41
Second Decision
2018-09-12 10:41
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-10-10 13:24
Articles in Press
2018-10-10 13:24
Publication Fee Transferred
Edit the Manuscript by Language Editor
2018-10-22 04:53
Typeset the Manuscript
2018-11-22 01:46
Publish the Manuscript Online
2018-11-27 13:56
ISSN 1948-5182 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Editorial
Article Title Exosomal microRNAs as a potential therapeutic strategy in hepatocellular carcinoma
Manuscript Source Invited Manuscript
All Author List Angélique Gougelet
ORCID
Author(s) ORCID Number
Angélique Gougelet http://orcid.org/0000-0001-7464-9804
Funding Agency and Grant Number
Corresponding Author Angélique Gougelet, PhD, Research Scientist, Inserm, U1016, Institut Cochin, 24, rue du Faubourg Saint Jacques, Paris 75014, France. angelique.gougelet@inserm.fr
Key Words MicroRNAs; Hepatocellular carcinoma; Targeted therapy; Exosomes
Core Tip Despite the intensive research efforts to identify the molecular events responsible for the em­ergence of liver cancer, hepatocellular carcinoma (HCC) remains a major health problem worldwide. Thus, the identification of new therapeutic opportunities to counteract the challenging issues linked to HCC hete­rogeneity and resistance to conventional treatments is a short-term necessity. Over the last few decades, microRNAs have appeared as interesting therapeutic strategies with their pleiotropic inhibitory action, but the use of a delivery system is a requirement for miRNA mimic administration. Exosomes, which are small vesi­cles naturally produced by immune cells and aberrantly by cancer cells, have recently emerged as a promising vehicle.
Publish Date 2018-11-27 13:56
Citation Gougelet A. Exosomal microRNAs as a potential therapeutic strategy in hepatocellular carcinoma. World J Hepatol 2018; 10(11): 785-789
URL http://www.wjgnet.com/1948-5182/full/v10/i11/785.htm
DOI http://dx.doi.org/10.4254/wjh.v10.i11.785
Full Article (PDF) WJH-10-785.pdf
Full Article (Word) WJH-10-785.doc
Manuscript File 41335-Review.docx
Answering Reviewers 41335-Answering reviewers.pdf
Audio Core Tip 41335-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 41335-Conflict-of-interest statement.pdf
Copyright License Agreement 41335-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 41335-Language certificate.pdf
Peer-review Report 41335-Peer-review(s).pdf
Scientific Misconduct Check 41335-Scientific misconduct check.pdf
Scientific Editor Work List 41335-Scientific editor work list.pdf