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1/21/2019 9:20:19 AM | Browse: 883 | Download: 1073
Publication Name World Journal of Gastrointestinal Pharmacology and Therapeutics
Manuscript ID 41906
Country United States
Received
2018-10-19 04:44
Peer-Review Started
2018-10-19 08:53
To Make the First Decision
2018-11-16 02:18
Return for Revision
2018-11-28 00:36
Revised
2018-12-06 18:27
Second Decision
2019-01-08 11:24
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-01-09 21:31
Articles in Press
2019-01-09 21:31
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-01-18 06:26
Publish the Manuscript Online
2019-01-21 09:20
ISSN 2150-5349 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Case Report
Article Title Ipilimumab and Nivolumab induced steroid-refractory colitis treated with infliximab: A case report
Manuscript Source Unsolicited Manuscript
All Author List Ammar B Nassri, Valery Muenyi, Ahmad Alkhasawneh, Bruno De Souza Ribeiro, James S Scolapio, Miguel Malespin and Silvio W de Melo Jr
ORCID
Author(s) ORCID Number
Ammar B Nassri http://orcid.org/0000-0002-2068-939X
Valery Muenyi http://orcid.org/0000-0001-9990-7259
Ahmad Alkhasawneh http://orcid.org/0000-0002-1343-2035
Bruno De Souza Ribeiro http://orcid.org/0000-0001-7205-0304
James S Scolapio http://orcid.org/0000-0001-8913-9970
Miguel Malespin http://orcid.org/0000-0002-7804-5773
Silvio W de Melo Jr http://orcid.org/0000-0002-5046-5944
Funding Agency and Grant Number
Corresponding Author Ammar B Nassri, MD, Academic Fellow, Department of Medicine; Division of Gastroenterology and Hepatology, University of Florida at Jacksonville, 655 W 8th St, Jacksonville, Florida 32209, United States. anassri@gmail.com
Key Words Colitis; Infliximab; Biologics; Immune mediated adverse events; Ipilimumab; Nivolumab; Case report
Core Tip A variety of immune-modulating drugs are becoming increasingly used for various cancers. Despite increasing indications and improved efficacy, they are often associated with a wide variety of immune mediated adverse events. We report the first case of metastatic renal cell cancer treated with the anti-CTLA-4 monoclonal antibody Ipilimumab and the immune checkpoint inhibitor Nivolumab to develop severe steroid-refractory colitis, and describe its resolution after treatment with Infliximab.
Publish Date 2019-01-21 09:20
Citation Nassri AB, Muenyi V, AlKhasawneh A, Ribeiro BDS, Scolapio JS, Malespin M, de Melo Jr SW. Ipilimumab and Nivolumab induced steroid-refractory colitis treated with infliximab: A case report. World J Gastrointest Pharmacol Ther 2019; 10(1): 29-34
URL https://www.wjgnet.com/2150-5349/full/v10/i1/29.htm
DOI https://dx.doi.org/10.4292/wjgpt.v10.i1.29
Full Article (PDF) WJGPT-10-29.pdf
Full Article (Word) WJGPT-10-29.docx
CARE Checklist–2016 41906-CARE-Checklist–2016.pdf
Manuscript File 41906-Review.doc
Answering Reviewers 41906-Answering reviewers.pdf
Audio Core Tip 41906-Audio core tip.wav
Conflict-of-Interest Disclosure Form 41906-Conflict-of-interest statement.pdf
Copyright License Agreement 41906-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 41906-Informed consent statement.pdf
Peer-review Report 41906-Peer-review(s).pdf
Scientific Misconduct Check 41906-Scientific misconduct check.pdf
Scientific Editor Work List 41906-Scientific editor work list.pdf