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Articles Published Processes
12/14/2018 1:19:57 AM | Browse: 957 | Download: 1362
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Received |
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2018-09-01 03:23 |
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Peer-Review Started |
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2018-09-03 01:21 |
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First Decision by Editorial Office Director |
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2018-10-16 05:17 |
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Return for Revision |
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2018-10-17 06:32 |
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Revised |
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2018-10-23 16:23 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2018-11-23 11:05 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2018-11-26 22:14 |
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Articles in Press |
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2018-11-26 22:14 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2018-12-03 06:18 |
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Publish the Manuscript Online |
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2018-12-14 01:19 |
| ISSN |
1948-9358 (online) |
| Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Minireviews |
| Article Title |
Unexpected alliance between syndecan-1 and innate-like T cells to protect host from autoimmune effects of interleukin-17
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Anil Kumar Jaiswal, Mohanraj Sadasivam and Abdel Rahim A Hamad |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Abdel Rahim A Hamad, PhD, Associate Professor, Department of Pathology, School of Medicine, Johns Hopkins University, Ross 66G, 720 Rutland Ave, Baltimore, MD 21205, United States. ahamad@jhmi.edu |
| Key Words |
Natural killer T cell; Natural killer T 17 cells; Tγδ17 cells; Syndecan-1; Interleukin-17 |
| Core Tip |
Core tip: Interleukin-17 (IL-17) is a potent proinflammatory cytokine that plays a critical role in host defense against fungi and extracellular bacteria. Excessive production of IL-17, however, has been implicated in pathogenesis of many autoimmune diseases. Our recent findings show that natural killer T (NKT) cells and γδ T cells employ syndecan-1 (sdc1), a heparan sulfate proteoglycan that is predominantly expressed by epithelia, to prevent out of control expansion of IL-17-producing subsets of NKT (NKT17) cell and γδ (Tγδ17) cells. In this mini-review, we highlight these findings and briefly discuss their significance for developing new strategies to prevent IL-17-mediated autoimmme diseases. |
| Publish Date |
2018-12-14 01:19 |
| Citation |
Jaiswal AK, Sadasivam M, Hamad ARA. Unexpected alliance between syndecan-1 and innate-like T cells to protect host from autoimmune effects of interleukin-17. World J Diabetes 2018; 9(12): 220-225 |
| URL |
https://www.wjgnet.com/1948-9358/full/v9/i12/220.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v9.i12.220 |
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