Publication Name	World Journal of Experimental Medicine
Manuscript ID	41947
Country	Brazil

Received	2018-09-07 01:17
Peer-Review Started	2018-09-07 05:02
First Decision by Editorial Office Director	2018-10-19 01:33
Return for Revision	2018-10-23 01:41
Revised	2018-10-29 14:53
Publication Fee Transferred
Second Decision by Editor	2019-01-03 10:40
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2019-01-06 05:16
Articles in Press	2019-01-06 05:16
Edit the Manuscript by Language Editor
Typeset the Manuscript	2019-01-16 05:36
Publish the Manuscript Online	2019-01-16 08:14

ISSN	2220-315x (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Immunology
Manuscript Type	Minireviews
Article Title	Sirtuins in B lymphocytes metabolism and function
Manuscript Source	Invited Manuscript
All Author List	Bruno Ghirotto, Fernanda Fernades Terra, Niels Olsen Saraiva Camara and Paulo Jose Basso
ORCID	Author(s) ORCID Number Bruno Ghirotto http://orcid.org/0000-0001-6835-3329 Fernanda Fernades Terra http://orcid.org/0000-0002-2860-5365 Niels Olsen Saraiva Camara http://orcid.org/0000-0001-5436-1248 Paulo Jose Basso http://orcid.org/0000-0003-4856-9207
Funding Agency and Grant Number	Funding Agency Grant Number FAPESP 2015/26682-6 FAPESP 2017/03248-4 FAPESP 2017/05264-7
Corresponding Author	Niels Olsen Saraiva Camara, MD, PhD, Research Scientist, Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1730 Cid. Universitaria., Sao Paulo 05508-000, Sao Paulo, Brazil. niels@icb.usp.br
Key Words	B cells; Metabolic sensors; Histone deacetylases; Cancer
Core Tip	Current studies have focused on understanding which intracellular molecules coordinate the metabolic flux within the cells. In addition to metabolism, sirtuins play a role in virtually all cell biological processes, but they have not been properly described in B lymphocytes function and metabolism, despite the importance of these immune cells in health and disease. Here we discuss studies that associate sirtuins and B lymphocytes, highlight the gaps found in the literature and point out the future research directions.point out the future research directions.
Publish Date	2019-01-16 08:14
Citation	Ghirotto B, Terra FF, Câmara NO, Basso PJ. Sirtuins in B lymphocytes metabolism and function. World J Exp Med 2019; 9(1): 1-13
URL	https://www.wjgnet.com/2220-315X/full/v9/i1/1.htm
DOI	https://dx.doi.org/10.5493/wjem.v9.i1.1

Full Article (PDF)	WJEM-9-1.pdf
Full Article (Word)	WJEM-9-1.docx
Manuscript File	41947-Review.docx
Answering Reviewers	41947-Answering reviewers.pdf
Audio Core Tip	41947-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	41947-Conflict-of-interest statement.pdf
Copyright License Agreement	41947-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	41947-Non-Native-Speakers-of-English-Editing-Certificate-revision.pdf
Peer-review Report	41947-Review.docx
Peer-review Report	41947-Peer-review(s).pdf
Scientific Misconduct Check	41947-Scientific misconduct check.pdf
Scientific Editor Work List	41947-Scientific editor work list.pdf