Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	4200
Country	Japan

Received	2013-06-21 09:22
Peer-Review Started	2013-06-21 16:40
To Make the First Decision	2013-07-19 08:57
Return for Revision	2013-07-20 23:00
Revised
Second Decision	2013-08-16 19:51
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-08-17 00:41
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-08-28 17:13
Publish the Manuscript Online	2013-09-05 13:11

ISSN	1948-5204 (online)
Open Access
Copyright
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Cholangiocarcinoma developed in a patient with IgG4-related disease
Manuscript Source	Invited Manuscript
All Author List	Akitoshi Douhara, Akira Mitoro, Emi Otani, Masanori Furukawa, Kosuke Kaji, Masakazu Uejima, Masayoshi Sawai, Motoyuki Yoshida, Hitoshi Yoshiji, Junichi Yamao and Hiroshi Fukui
Funding Agency and Grant Number
Corresponding Author	Akitoshi Douhara, MD, Department of Gastroenterology and Endocrinology, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634-8521, Japan. aki-do@hotmail.co.jp
Key Words	IgG4; Sclerosing cholangitis; Autoimmune pancreatitis; Cholangiocarcinoma
Core Tip	Chronic biliary inflammation and cholestasis are risk factors for cholangiocarcinoma. However, an association of IgG4-related sclerosing cholangitis with cholangiocarcinoma has not been previously demonstrated. To date, only two report described have neoplasia in the bile duct in patients with IgG4-related sclerosing cholangitis. Risk factors for cholangiocarcinoma include chronic biliary inflammation and cholestasis, both of which can contribute to the malignant transformation of cholangiocytes in patients with sclerosing cholangitis. Because of a long duration of overt IgG4-related sclerosing cholangitis and the affected location of the patient’s cholangiocarcinoma, we presumed a cause-and-effect relationship between the sclerosing cholangitis and bile duct cancer.
Publish Date	2013-09-05 13:11
Citation	Douhara A, Mitoro A, Otani E, Furukawa M, Kaji K, Uejima M, Sawai M, Yoshida M, Yoshiji H, Yamao J, Fukui H. Cholangiocarcinoma developed in a patient with IgG4-related disease. World J Gastrointest Oncol 2013; 5(8): 181-185
URL	http://www.wjgnet.com/1948-5204/full/v5/i8/181.htm
DOI	http://dx.doi.org/10.4251/wjgo.v5.i8.181

Full Article (PDF)	WJGO-5-181.pdf
Manuscript File	4200-Review.docx
Answering Reviewers	4200-Answering reviewers.pdf
Copyright License Agreement	4200-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	4200-Language certificate.pdf
Peer-review Report	4200-Peer review(s).pdf
Scientific Editor Work List	4200-Scientific editor work list.doc