Publication Name	World Journal of Clinical Cases
Manuscript ID	42761
Country	China

Received	2018-10-15 02:04
Peer-Review Started	2018-10-15 06:46
To Make the First Decision	2018-11-14 04:00
Return for Revision	2018-11-15 02:32
Revised	2018-11-22 08:40
Second Decision	2018-11-30 08:21
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2018-12-01 03:16
Articles in Press	2018-12-01 03:16
Publication Fee Transferred
Edit the Manuscript by Language Editor	2018-12-05 13:28
Typeset the Manuscript	2018-12-13 03:30
Publish the Manuscript Online	2018-12-24 01:07

ISSN	2307-8960 (online)
Open Access
Copyright	© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Medicine, Research & Experimental
Manuscript Type	Retrospective Study
Article Title	Safety of fecal microbiota transplantation in chinese children: A single-center retrospective study
Manuscript Source	Unsolicited Manuscript
All Author List	Xin-Yue Zhang, Yi-Zhong Wang, Xiao-Lu Li, Hui Hu, Hai-Feng Liu, Dan Li, Yong-Mei Xiao and Ting Zhang
ORCID	Author(s) ORCID Number Xin-Yue Zhang http://orcid.org/0000-0002-4821-9795 Yi-Zhong Wang http://orcid.org/0000-0002-9390-8864 Xiao-Lu Li http://orcid.org/0000-0003-3057-3320 Hui Hu http://orcid.org/0000-0001-6544-3070 Hai-Feng Liu http://orcid.org/0000-0002-5620-5000 Dan Li http://orcid.org/0000-0002-5518-8421 Yong-Mei Xiao http://orcid.org/0000-0002-1591-7490 Ting Zhang http://orcid.org/0000-0001-9391-8926
Funding Agency and Grant Number	Funding Agency Grant Number Shanghai Hospital Development Center New Frontier Technology Joint Research Project SHDC12017115
Corresponding Author	Ting Zhang, PhD, Professor, Department of Gastroenterology, Hepatology and Nutrition, Shanghai Children's Hospital, Shanghai Jiao Tong University, No. 355 Luding Road, Shanghai 200062, China. zhangt@shchildren.com.cn
Key Words	Safety; Fecal microbiota transplantation; Pediatrics; Adverse event; Immune system diseases; Age factors
Core Tip	A retrospective study was conducted on 49 patients who underwent 114 fecal microbiota trans-plantation (FMT) treatments at our hospital. The safety of FMT was evaluated by short-term, long-term, and severe adverse events (AEs). The incidence of short-term AEs was 26.32% (30/114). The most common short-term AEs were abdominal pain, diarrhea, fever, and vomiting. Age and immune state had significant effects, and immune state was an independent risk factor for AEs occurrence. The risk ratio in immuno¬deficient patients was 3.105. Pediatricians need to be more cautious when FMT is applied to immunodeficient patients.
Publish Date	2018-12-24 01:07
Citation	Zhang XY, Wang YZ, Li XL, Hu H, Liu HF, Li D, Xiao YM, Zhang T. Safety of fecal microbiota transplantation in Chinese children: A single-center retrospective study. World J Clin Cases 2018; 6(16): 1121-1127
URL	https://www.wjgnet.com/2307-8960/full/v6/i16/1121.htm
DOI	https://dx.doi.org/10.12998/wjcc.v6.i16.1121

Full Article (PDF)	WJCC-6-1121.pdf
Full Article (Word)	WJCC-6-1121.doc
Manuscript File	42761-Review.docx
Answering Reviewers	42761-Answering reviewers.pdf
Audio Core Tip	42761-Audio core tip.mp3
Biostatistics Review Certificate	42761-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	42761-Conflict-of-interest statement.pdf
Copyright License Agreement	42761-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	42761-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	42761-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	42761-Language certificate.pdf
Peer-review Report	42761-Peer-review(s).pdf
Scientific Misconduct Check	42403-Scientific misconduct check.pdf
Scientific Editor Work List	42761-Scientific editor work list.pdf