Publication Name	World Journal of Clinical Cases
Manuscript ID	42936
Country	China

Received	2018-10-25 08:16
Peer-Review Started	2018-10-26 02:55
To Make the First Decision	2018-11-20 10:29
Return for Revision	2018-11-28 03:21
Revised	2018-12-27 09:33
Second Decision	2019-01-03 11:51
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2019-01-03 23:50
Articles in Press	2019-01-03 23:50
Publication Fee Transferred
Edit the Manuscript by Language Editor	2019-01-08 01:57
Typeset the Manuscript	2019-01-25 09:12
Publish the Manuscript Online	2019-01-26 08:24

ISSN	2307-8960 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Medicine, Research & Experimental
Manuscript Type	Systematic Reviews
Article Title	Clinical significance of exosomes as potential biomarkers in cancer
Manuscript Source	Invited Manuscript
All Author List	Chi-Hin Wong and Yang-Chao Chen
ORCID	Author(s) ORCID Number Chi-Hin Wong http://orcid.org/0000-0002-9070-193X Yang-Chao Chen http://orcid.org/0000-0002-0249-3414
Funding Agency and Grant Number
Corresponding Author	Yang-Chao Chen, PhD, School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong , China. yangchaochen@cuhk.edu.hk
Key Words	Exosome; Biomarker; Cancer; Diagnosis; Prognosis
Core Tip	Cancer-derived exosomes carry a wide variety of DNA, RNA, proteins and lipids, which may serve as novel biomarkers in cancer. The current systematic review and meta-analysis summarized the performance of exosomal biomarkers in cancer diagnosis and prognosis. We analyzed 47 diagnostic markers and 50 prognostic markers from 56 studies with various type of cancer. We found that exosomal biomarkers had both diagnostic and prognostic power in many cancers.
Publish Date	2019-01-26 08:24
Citation	Wong CH, Chen YC. Clinical significance of exosomes as potential biomarkers in cancer. World J Clin Cases 2019; 7(2): 171-190
URL	https://www.wjgnet.com/2307-8960/full/v7/i2/171.htm
DOI	https://dx.doi.org/10.12998/wjcc.v7.i2.171

Full Article (PDF)	WJCC-7-171.pdf
Full Article (Word)	WJCC-7-171.docx
PRISMA 2009 Checklist	42936-PRISMA 2009 Checklist statement.pdf
Manuscript File	42936-Review.docx
Answering Reviewers	42936-Answering reviewers.pdf
Audio Core Tip	42936-Audio core tip.m4a
Biostatistics Review Certificate	42936-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	42936-Conflict-of-interest statement.pdf
Copyright License Agreement	42936-Copyright license agreement.pdf
Peer-review Report	42936-Peer-review(s).pdf
Scientific Misconduct Check	42936-Scientific misconduct check.pdf
Scientific Editor Work List	42936-Scientific editor work list.pdf