Publication Name	World Journal of Orthopedics
Manuscript ID	4308
Country	Egypt

Received	2013-06-28 08:29
Peer-Review Started	2013-06-28 13:59
To Make the First Decision	2013-07-05 18:36
Return for Revision	2013-07-08 16:26
Revised
Second Decision	2013-08-29 07:59
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-08-29 10:12
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2013-09-08 13:19
Typeset the Manuscript	2013-09-17 09:15
Publish the Manuscript Online	2013-10-28 15:24

ISSN	2218-5836 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Orthopedics
Manuscript Type	Review
Article Title	Healing of subcutaneous tendons: Influence of the mechanical environment at the suture line on the healing process
Manuscript Source	Invited Manuscript
All Author List	Elsayed Ibraheem Elsayed Massoud
Funding Agency and Grant Number
Corresponding Author	Elsayed Ibraheem Elsayed Massoud, MD, Orthopaedic Department, Sohag Teaching Hospital, General Organization for Teaching Hospitals and Institutes, Nile St., 82521 Tahta, Sohag, Egypt. elsayedmassoud@hotmail.com
Key Words	Tendon; Healing; Mechanical loading; Mechanotransduction; Rupture; Repair
Core Tip	Ruptured tendons heal poorly compared to skin, muscles and bones. Immobilization during repair has been shown to be detrimental for the healing process. Mechanical loading of the tendon callus gives rise to intracellular signaling, increases gene expression and protein synthesis. However, early loading reported clinical complications. A surgical technique based on control of the mechanical environment at the suture line provided satisfactory results. Therefore, understanding the interplay between loading and the healing process seems necessary. This review focuses on the biological processes that regulate tendon repair and timing of mechanical loading during the healing process. How do tendon cells sense mechanical forces?
Publish Date	2013-10-28 15:24
Citation	Massoud EIE. Healing of subcutaneous tendons: Influence of the mechanical environment at the suture line on the healing process. World J Orthop 2013; 4(4): 229-240
URL	http://www.wjgnet.com/2218-5836/full/v4/i4/229.htm
DOI	http://dx.doi.org/10.5312/wjo.v4.i4.229

Full Article (PDF)	WJO-4-229.pdf
Manuscript File	4308-Review.docx
Answering Reviewers	4308-Answering reviewers.pdf
Copyright License Agreement	4308-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	4308-Language certificate.pdf
Peer-review Report	4308-Peer review(s).pdf
Scientific Editor Work List	4308-Scientific editor work list.doc