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Publication Name World Journal of Diabetes
Manuscript ID 43124
Country/Territory United States
2018-10-25 08:05
Peer-Review Started
2018-10-25 09:09
To Make the First Decision
2018-12-11 01:17
Return for Revision
2018-12-11 09:53
2019-01-04 01:47
Second Decision
2019-01-08 10:38
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-01-08 18:57
Articles in Press
2019-01-08 18:57
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-01-15 06:25
Publish the Manuscript Online
2019-01-16 05:53
ISSN 1948-9358 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Endocrinology and Metabolism
Manuscript Type Minireviews
Article Title Exploratory metabolomics of metabolic syndrome: A status report
Manuscript Source Invited Manuscript
All Author List Daniella Lent-Schochet, Matthew McLaughlin, Neeraj Ramakrishnan and Ishwarlal Jialal
Author(s) ORCID Number
Daniella Lent-Schochet http://orcid.org/0000-0002-3165-7932
Matthew McLaughlin http://orcid.org/0000-0002-4471-4246
Neeraj Ramakrishnan http://orcid.org/0000-0002-9011-2959
Ishwarlal Jialal http://orcid.org/0000-0001-9113-2604
Funding Agency and Grant Number
Corresponding author Ishwarlal Jialal, MD, PhD, College of Medicine, California North-state University, 9700 West Taron Drive, Elk Grove, CA 95757, United States. ishwarlal.jialal@cnsu.edu
Keywords Metabolic syndrome; Syndrome X, Metabolomics; Amino acids; Carnitine; Inflammation; Biomarkers; Diabetes
Core Tip Metabolic syndrome (MetS) is a global epidemic that predisposes to type II diabetes mellitus, atherosclerotic cardiovascular disease and increased mortality. Whilst both insulin resistance and inflammation are advanced as pathogenic mechanisms, much work is needed to identify reliable biomarkers for this common cardio-metabolic disorder. In this mini-review, we provide a status report on the evolving field of metabolomics in MetS and it appears to offer some promising biomarkers such as branched chain amino acids, lysine, carnitine, phosphatidylcholine (PC34:1) and PC34:2. However there is an urgent need to direct greater effort to the metabolome of MetS to unravel its pathopysiology and usher in much needed therapeutics.
Publish Date 2019-01-16 05:53
Citation Lent-Schochet D, McLaughlin M, Ramakrishnan N, Jialal I. Exploratory metabolomics of metabolic syndrome: A status report. World J Diabetes 2019; 10(1): 23-36
Url https://www.wjgnet.com/1948-9358/full/v10/i1/23.htm
DOI https://dx.doi.org/10.4239/wjd.v10.i1.23
Full Article (PDF) WJD-10-23.pdf
Full Article (Word) WJD-10-23.docx
Manuscript File 43124-Review.docx
Answering Reviewers 43124-Answering reviewers.pdf
Audio Core Tip 43124-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 43124-Conflict-of-interest statement.pdf
Copyright License Agreement 43124-Copyright license agreement.pdf
Peer-review Report 43124-Peer-review(s).pdf
Scientific Misconduct Check 43124-Scientific misconduct check.pdf
Scientific Editor Work List 43124-Scientific editor work list.pdf