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Articles Published Processes
1/16/2019 5:53:40 AM | Browse: 951 | Download: 1184
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Received |
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2018-10-25 08:05 |
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Peer-Review Started |
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2018-10-25 09:09 |
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To Make the First Decision |
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2018-12-11 01:17 |
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Return for Revision |
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2018-12-11 09:53 |
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Revised |
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2019-01-04 01:47 |
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Second Decision |
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2019-01-08 10:38 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2019-01-08 18:57 |
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Articles in Press |
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2019-01-08 18:57 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-01-15 06:25 |
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Publish the Manuscript Online |
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2019-01-16 05:53 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Minireviews |
| Article Title |
Exploratory metabolomics of metabolic syndrome: A status report
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Daniella Lent-Schochet, Matthew McLaughlin, Neeraj Ramakrishnan and Ishwarlal Jialal |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Ishwarlal Jialal, MD, PhD, College of Medicine, California North-state University, 9700 West Taron Drive, Elk Grove, CA 95757, United States. ishwarlal.jialal@cnsu.edu |
| Key Words |
Metabolic syndrome; Syndrome X, Metabolomics; Amino acids; Carnitine; Inflammation; Biomarkers; Diabetes |
| Core Tip |
Metabolic syndrome (MetS) is a global epidemic that predisposes to type II diabetes mellitus, atherosclerotic cardiovascular disease and increased mortality. Whilst both insulin resistance and inflammation are advanced as pathogenic mechanisms, much work is needed to identify reliable biomarkers for this common cardio-metabolic disorder. In this mini-review, we provide a status report on the evolving field of metabolomics in MetS and it appears to offer some promising biomarkers such as branched chain amino acids, lysine, carnitine, phosphatidylcholine (PC34:1) and PC34:2. However there is an urgent need to direct greater effort to the metabolome of MetS to unravel its pathopysiology and usher in much needed therapeutics. |
| Publish Date |
2019-01-16 05:53 |
| Citation |
Lent-Schochet D, McLaughlin M, Ramakrishnan N, Jialal I. Exploratory metabolomics of metabolic syndrome: A status report. World J Diabetes 2019; 10(1): 23-36 |
| URL |
https://www.wjgnet.com/1948-9358/full/v10/i1/23.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v10.i1.23 |
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