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9/15/2014 4:56:00 PM | Browse: 995 | Download: 1021
Publication Name World Journal of Respirology
Manuscript ID 4316
Country Japan
Received
2013-06-27 10:28
Peer-Review Started
2013-06-27 16:18
To Make the First Decision
2013-07-05 18:36
Return for Revision
2013-07-09 10:48
Revised
2013-07-12 18:04
Second Decision
2013-07-18 14:50
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-07-19 01:11
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2013-11-26 13:27
Publish the Manuscript Online
2013-12-03 15:44
ISSN 2218-6255 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Minireviews
Article Title FDG-PET for predicting efficacy of EGFR-tyrosine kinase inhibitors in lung cancer
Manuscript Source Invited Manuscript
All Author List Noriaki Sunaga, Kyoichi Kaira, Takeshi Hisada and Masanobu Yamada
Funding Agency and Grant Number
Corresponding Author Noriaki Sunaga, MD, Department of Medicine and Molecular Science, Gunma University Graduat School of Medicine, 3-39-15, Showa-machi, Maebashi, Gunma 371-8511, Japan. nsunaga@gunma-u.ac.jp
Key Words Non-small cell lung cancer; 18F-fluorodeoxyglucose measured by positron emission tomography; Epidermal growth factor receptor mutation; Gefitinib; Erlotinib; Survival; Biomarker
Core Tip Molecularly targeted drugs including epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs), which usually exhibit cytostatic antitumor activity, have emerged for the treatment of non-small cell lung cancer. The Response Evaluation Criteria in Solid Tumors is generally used to assess the therapeutic response based on the morphological changes in tumor size as evaluated by computed tomography or magnetic resonance imaging. However, such assessment may not always reflect the clinical outcome of cytostatic drugs, such as EGFR-TKIs. In this regard, 18F-fluorodeoxyglucose measured by positron emission tomography (FDG-PET) is potentially beneficial. Here we summarize the role of FDG-PET to predict the treatment efficacy in NSCLC treated with EGFR-TKIs.
Publish Date 2013-12-03 15:44
Citation Sunaga N, Kaira K, Hisada T, Yamada M. FDG-PET for predicting efficacy of EGFR-tyrosine kinase inhibitors in lung cancer. World J Respirol 2013; 3(3): 104-109
URL http://www.wjgnet.com/2218-6255/full/v3/i3/104.htm
DOI http://dx.doi.org/10.5320/wjr.v3.i3.104
Full Article (PDF) WJR-3-104.pdf
Manuscript File 4316-Review.docx
Answering Reviewers 4316-Answering reviewers.pdf
Copyright License Agreement 4316-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 4316-Language certificate.pdf
Peer-review Report 4316-Peer review(s).pdf
Scientific Editor Work List 4316-Scientific editor work list.doc