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Articles Published Processes
3/7/2019 3:51:24 AM | Browse: 1272 | Download: 2087
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Received |
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2018-10-30 01:55 |
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Peer-Review Started |
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2018-11-01 01:01 |
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To Make the First Decision |
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2018-12-05 05:59 |
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Return for Revision |
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2018-12-17 07:06 |
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Revised |
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2019-02-15 06:43 |
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Second Decision |
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2019-02-15 09:36 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-02-16 02:56 |
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Articles in Press |
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2019-02-16 02:56 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-03-06 09:14 |
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Publish the Manuscript Online |
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2019-03-07 03:51 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Clinical Trials Study |
| Article Title |
Comprehensive lifestyle intervention vs soy protein-based meal regimen in non-alcoholic steatohepatitis
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Peter Deibert, Adhara Lazaro, Denise Schaffner, Aloys Berg, Daniel Koenig, Wolfgang Kreisel, Manfred W Baumstark, Daniel Steinmann, Martin Buechert and Thomas Lange |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Almased® Wellness Company, Bienenbuettel, Germany |
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| Corresponding Author |
Peter Deibert, MD, Professor, Institute for Exercise and Occupational Medicine, Faculty of Medicine, Medical Center-University of Freiburg, Hugstetter Str. 55, Freiburg 79106, Germany. peter.deibert@uniklinik-freiburg.de |
| Key Words |
Non-alcoholic steatohepatitis; Meal replacement therapy; Soy protein; Lifestyle change; Weight reduction; Obesity |
| Core Tip |
Non-alcoholic steatohepatitis (NASH) is a major cause of chronic liver disease. In obese patients weight reduction is recommended. We studied the effect of a soy protein-based meal replacement therapy and a therapeutic lifestyle intervention in a randomized controlled study of obese patients with NASH. Both groups significantly lost body fat and liver fat while muscle mass remained stable. Corresponding changes were found in blood lipids and adipokines. However, liver fat quality as mean chain length and saturation of lipids was modified differently by each intervention. The relevance of these findings has to be cleared by further studies. |
| Publish Date |
2019-03-07 03:51 |
| Citation |
Deibert P, Lazaro A, Schaffner D, Berg A, Koenig D, Kreisel W, Baumstark MW, Steinmann D, Buechert M, Lange T. Comprehensive lifestyle intervention vs soy protein-based meal regimen in non-alcoholic steatohepatitis. World J Gastroenterol 2019; 25(9): 1116-1131 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i9/1116.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i9.1116 |
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