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1/29/2019 2:00:23 AM | Browse: 1128 | Download: 1395
Publication Name World Journal of Clinical Cases
Manuscript ID 43221
Country/Territory Romania
Received
2018-10-30 01:53
Peer-Review Started
2018-10-31 02:26
To Make the First Decision
2018-11-16 01:07
Return for Revision
2018-11-29 07:06
Revised
2018-12-18 19:16
Second Decision
2018-12-21 09:02
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-12-24 02:38
Articles in Press
2018-12-24 02:38
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-01-25 05:27
Publish the Manuscript Online
2019-01-29 02:00
ISSN 2307-8960 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, Research & Experimental
Manuscript Type Prospective Study
Article Title Split-dose or hybrid nonsteroidal anti-inflammatory drugs and N-acetylcysteine therapy for prevention of post-retrograde cholangiopancreatography pancreatitis
Manuscript Source Invited Manuscript
All Author List Laura Pavel, Gheorghe Gh Bălan, Alexandra Nicorescu, Georgiana Emmanuela Gîlcă-Blanariu, Cătălin Sfarti, Ștefan Chiriac, Smaranda Diaconescu, Vasile Liviu Drug, Gheorghe Bălan and Gabriela Ștefănescu
ORCID
Author(s) ORCID Number
Laura Pavel http://orcid.org/0000-0003-2194-4345
Gheorghe Gh Bălan http://orcid.org/0000-0001-9789-8280
Alexandra Nicorescu http://orcid.org/0000-0002-1090-9520
Georgiana Emmanuela Gîlcă-Blanariu http://orcid.org/0000-0002-5590-6462
Cătălin Sfarti http://orcid.org/0000-0001-7074-5938
Ștefan Chiriac http://orcid.org/0000-0003-2497-9236
Smaranda Diaconescu http://orcid.org/0000-0001-8018-7191
Vasile Liviu Drug http://orcid.org/0000-0002-7596-2656
Gheorghe Bălan http://orcid.org/0000-0002-2919-4940
Gabriela Ștefănescu http://orcid.org/0000-0002-1394-8648
Funding Agency and Grant Number
Corresponding Author Smaranda Diaconescu, MD, PhD, Associate Professor, Department of Mother and Child Medicine, “Grigore T. Popa” University Of Medicine and Pharmacy, 16 Universității str, Iasi 700115, Romania. turti23@yahoo.com
Key Words Endoscopic retrograde cholangiopancreatography; Prophylaxis; Post-ERCP pancreatitis; Nonsteroidal anti-inflammatory drugs; N-acetylcysteine
Core Tip Despite significant technical and training improvements, the incidence of post-endoscopic retrograde-cholangiopancreatography (ERCP) pancreatitis has not dropped significantly. The present prospective, single-center randomized trial aimed to evaluate the efficacy of three prophylactic approaches for preventing post-ERCP pancreatitis. The results obtained demonstrate that the efficacies for preventing post-ERCP pancreatitis for both split-dose administration of indomethacin and combined administration of N-acetylcysteine before the procedure with administration of indomethacin post-ERCP are similar to that of the guideline-recommended regimen; although, a slightly more rapid improvement in the biological response was observed for the study group receiving the combination therapy (nonsteroidal anti-inflammatory drugs associated with N-acetylcysteine).
Publish Date 2019-01-29 02:00
Citation Pavel L, Bălan GG, Nicorescu A, Gîlcă-Blanariu GE, Sfarti C, Chiriac Ș, Diaconescu S, Drug VL, Bălan G, Ștefănescu G. Split-dose or hybrid nonsteroidal anti-inflammatory drugs and N-acetylcysteine therapy for prevention of post-retrograde cholangiopancreatography pancreatitis. World J Clin Cases 2019; 7(3): 300-310
URL https://www.wjgnet.com/2307-8960/full/v7/i3/300.htm
DOI https://dx.doi.org/10.12998/wjcc.v7.i3.300
Full Article (PDF) WJCC-7-300.pdf
Full Article (Word) WJCC-7-300.docx
CONSORT 2010 Statement 43221-CONSORT 2010 statement.pdf
Manuscript File 43221-Review.docx
Answering Reviewers 43221-Answering reviewers.pdf
Audio Core Tip 43221-Audio core tip.mp3
Biostatistics Review Certificate 43221-Biostatistics statement.pdf
Clinical Trial Registration Statement 43221-Clinical trial registration statement.pdf
Conflict-of-Interest Disclosure Form 43221-Conflict-of-interest statement.pdf
Copyright License Agreement 43221-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 43221-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 43221-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 43221-Language certificate.pdf
Peer-review Report 43221-Peer-review(s).pdf
Scientific Misconduct Check 43221-Scientific misconduct check.pdf
Scientific Editor Work List 43221-Scientific editor work list.pdf