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Publication Name World Journal of Gastroenterology
Manuscript ID 43228
Country of Manuscript Source Italy
2018-11-05 03:01
Peer-Review Started
2018-11-05 09:26
To Make the First Decision
2018-12-20 06:47
Return for Revision
2018-12-20 08:59
2019-01-14 17:08
Second Decision
2019-01-18 11:25
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-01-18 23:05
Articles in Press
2019-01-18 23:05
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-01-25 02:24
Publish the Manuscript Online
2019-01-26 11:40
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Observational Study
Article Title Intestinal permeability after Mediterranean diet and low-fat diet in non-alcoholic fatty liver disease
Manuscript Source Invited Manuscript
All Author List Marco Biolato, Fiorella Manca, Giuseppe Marrone, Consuelo Cefalo, Simona Racco, Giacinto A.D. Miggiano, Venanzio Valenza, Antonio Gasbarrini, Luca Miele and Antonio Grieco
Author(s) ORCID Number
Marco Biolato http://orcid.org/0000-0002-5172-8208
Fiorella Manca http://orcid.org/0000-0002-8084-1437
Giuseppe Marrone http://orcid.org/000-0002-9475-3948
Consuelo Cefalo http://orcid.org/0000-0001-6589-7435
Simona Racco http://orcid.org/0000-0002-9033-9205
Giacinto A.D. Miggiano http://orcid.org/0000-0002-8627-5528
Venanzio Valenza http://orcid.org/0000-0002-0023-6625
Antonio Gasbarrini http://orcid.org/0000-0002-6230-1779
Luca Miele http://orcid.org/0000-0003-3464-0068
Antonio Grieco http://orcid.org/0000-0002-0544-8993
Funding Agency and Grant Number
Funding Agency Grant Number
This work was supported by a grant by the Italian Ministry of Education, University and Research (MIUR), scientific research programmes of relevant national interest (PRIN) year 2010-2011 2010C4JJWB
Corresponding author Marco Biolato, MD, PhD, Staff Physician, Liver Transplant Medicine, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo A. Gemelli 8, Rome 00168, Italy. marco.biolato@policlinicogemelli.it
Keywords Liver steatosis; Gut-liver axis; Nutrition; Personalized medicine; Visceral obesity
Core Tip Diet, as well as intestinal microbiota, is a key regulator of intestinal permeability, the alteration of which is central in the derangement of the gut-liver axis. In patients with non-alcoholic fatty liver disease (NAFLD), intestinal permeability is increased, promoting translocation of bacteria-derived products into the portal circulation and increasing hepatic exposure to injurious substances that stimulate hepatic inflammation and fibrosis in animal models, high-fat diet or high-fructose intake has been associated with increased gut permeability. The aim of this study was to detect diet-induced modification of intestinal permeability in non-diabetic patients with NAFLD undergoing a Mediterranean diet or a low-fat diet.
Publish Date 2019-01-26 11:40
Citation Biolato M, Manca F, Marrone G, Cefalo C, Racco S, Miggiano GA, Valenza V, Gasbarrini A, Miele L, Grieco A. Intestinal permeability after Mediterranean diet and low-fat diet in non-alcoholic fatty liver disease. World J Gastroenterol 2019; 25(4): 509-520
Url https://www.wjgnet.com/1007-9327/full/v25/i4/509.htm
DOI https://dx.doi.org/10.3748/wjg.v25.i4.509
Full Article (PDF) WJG-25-509.pdf
Full Article (Word) WJG-25-509.docx
Manuscript File 43228-Review.docx
Answering Reviewers 43228-Answering reviewers.pdf
Audio Core Tip 43228-Audio core tip.mp3
Biostatistics Review Certificate 43228-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 43228-Conflict-of-interest statement.pdf
Copyright License Agreement 43228-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 43228-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 43228-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 43228-Institutional review board statement.PDF
Non-Native Speakers of English Editing Certificate 43228-Language certificate.pdf
Supplementary Material 43228-Supplementary material.pdf
Peer-review Report 43228-Peer-review(s).pdf
Scientific Misconduct Check 43228-Scientific misconduct check.pdf
Scientific Editor Work List 43228-Scientific editor work list.pdf