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2/21/2019 9:31:55 AM | Browse: 185 | Download: 126
Publication Name World Journal of Gastroenterology
Manuscript ID 43267
Country of Manuscript Source China
2018-11-06 06:34
Peer-Review Started
2018-11-12 01:16
To Make the First Decision
2018-11-29 09:24
Return for Revision
2018-12-17 07:08
2019-01-10 02:28
Second Decision
2019-01-18 11:28
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-01-18 23:07
Articles in Press
2019-01-18 23:07
Publication Fee Transferred
Edit the Manuscript by Language Editor
2019-01-23 01:34
Typeset the Manuscript
2019-02-20 10:24
Publish the Manuscript Online
2019-02-21 09:31
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected byan in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Basic Study
Article Title Ubiquitin-specific protease 22 enhances intestinal cell proliferation and tissue regeneration after intestinal ischemia reperfusion injury
Manuscript Source Unsolicited Manuscript
All Author List An-Long Ji, Tong Li, Guo Zu, Dong-Cheng Feng, Yang Li, Guang-Zhi Wang, Ji-Hong Yao and Xiao-Feng Tian
Author(s) ORCID Number
An-Long Ji http://orcid.org/0000-0002-1224-186X
Tong Li http://orcid.org/0000-0002-9987-8256
Guo Zu http://orcid.org/0000-0002-6333-8573
Dong-Cheng Feng http://orcid.org/0000-0002-8356-1406
Yang Li http://orcid.org/0000-0003-1015-5447
Guang-Zhi Wang http://orcid.org/0000-0001-6744-4966
Ji-Hong Yao http://orcid.org/0000-0003-1890-8749
Xiao-Feng Tian http://orcid.org/0000-0001-9219-1868
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81679154
Corresponding author Xiao-Feng Tian, MD, PhD, Director, Professor, Surgeon, Department of General Surgery, The Second Affiliated Hospital of Dalian Medical University, 467 Zhongshan Road, Shahekou District, Dalian 116023, Liaoning Province, China. txfdl@dmu.edu.cn
Keywords Ubiquitin-specific protease 22; Proliferation; Regeneration; Repair; Intestinal ischemia-reperfusion
Core Tip The ubiquitin-specific protease 22 (USP22) belongs to the USPs family, which regulate cell cycle progression, proliferation, and tumor invasion. The depleted expression of USP22 has been linked to arrested cell cycle and disrupted distribution and generation of differentiated cell types in crypts and villi. However, its regulatory mechanism remains unclear. By generating models of ischemia reperfusion (I/R) injury and regulating USP22 expression levels, this study reveals USP22 is correlated with promoting intestinal cell proliferation and accelerating intestinal tissue regeneration after intestinal I/R injury. USP22 might serve as a potential target for therapeutic development for tissue repair during intestinal I/R injury.
Publish Date 2019-02-21 09:31
Citation Ji AL, Li T, Zu G, Feng DC, Li Y, Wang GZ, Yao JH, Tian XF. Ubiquitin-specific protease 22 enhances intestinal cell proliferation and tissue regeneration after intestinal ischemia reperfusion injury. World J Gastroenterol 2019; 25(7): 824-836
Url https://www.wjgnet.com/1007-9327/full/v25/i7/824.htm
DOI https://dx.doi.org/10.3748/wjg.v25.i7.824
Full Article (PDF) WJG-25-824.pdf
Full Article (Word) WJG-25-824.docx
Manuscript File 43267-Review_Edited.doc
Answering Reviewers 43267-Answering reviewers.pdf
Audio Core Tip 43267-Audio core tip.mp3
Biostatistics Review Certificate 43267-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 43267-Conflict-of-interest statement.pdf
Copyright License Agreement 43267-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 43267-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 43267-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 43267-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 43267-Language certificate.pdf
Peer-review Report 43267-Peer-review(s).pdf
Scientific Misconduct Check 43267-Scientific misconduct check.pdf
Scientific Editor Work List 43267-Scientific editor work list.pdf