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Articles Published Processes
4/25/2019 3:13:57 AM | Browse: 879 | Download: 1722
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Received |
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2018-11-10 08:37 |
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Peer-Review Started |
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2018-11-12 02:09 |
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To Make the First Decision |
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2018-12-29 00:53 |
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Return for Revision |
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2018-12-29 06:14 |
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Revised |
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2019-02-12 17:26 |
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Second Decision |
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2019-02-15 09:37 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-02-16 02:53 |
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Articles in Press |
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2019-02-16 02:53 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-04-17 09:19 |
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Publish the Manuscript Online |
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2019-04-25 03:13 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Assessment of chronic radiation proctopathy and radiofrequency ablation treatment follow-up with optical coherence tomography angiography: A pilot study
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Osman Oguz Ahsen, Kaicheng Liang, Hsiang-Chieh Lee, Zhao Wang, James G Fujimoto and Hiroshi Mashimo |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| VA Boston Healthcare System |
R01-CA075289-21 |
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| Corresponding Author |
Hiroshi Mashimo, MD, MSc, PhD, Associate Professor, Research Scientist, Gastroenterology Section, VA Boston Healthcare System, Harvard School of Medicine, 150 South Huntington Ave., Boston, MA 02130, United States. hmashimo@hms.harvard.edu |
| Key Words |
Optical coherence tomography; Optical coherence tomography angiography; Radiofrequency ablation; Chronic radiation proctopathy; Rectal telangiectasia density scoring system; Subsurface microvascular imaging |
| Core Tip |
In this study we use a prototype ultrahigh-speed optical coherence tomography (OCT) system and OCT angiography (OCTA) to perform depth-resolved visualization of microvasculature in the mucosal and submucosal layers of the rectum without requiring injected dyes. Abnormal distorted honeycomb patterns and ectatic/tortuous microvasculature in the rectal mucosa and heterogenous enlarged arterioles and venules > 200 μm in diameter in the submucosa are associated with chronic radiation proctopathy and resolved with radiofrequency ablation treatment. OCTA/OCT is a promising tool for investigating the pathophysiology of chronic radiation proctopathy and further studies are warranted to understand if it can help in clinical management. |
| Publish Date |
2019-04-25 03:13 |
| Citation |
Ahsen OO, Liang K, Lee HC, Wan Z, Fujimoto JG, Mashimo H. Assessment of chronic radiation proctopathy and radiofrequency ablation treatment follow-up with optical coherence tomography angiography: A pilot study. World J Gastroenterol 2019; 25(16): 1997-2009 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i16/1997.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i16.1997 |
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