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Articles Published Processes
2/27/2019 4:11:15 AM | Browse: 1026 | Download: 1957
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Received |
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2018-11-27 02:04 |
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Peer-Review Started |
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2018-11-27 03:08 |
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To Make the First Decision |
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2018-12-20 06:43 |
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Return for Revision |
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2018-12-20 08:46 |
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Revised |
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2019-01-22 08:18 |
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Second Decision |
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2019-01-25 10:18 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-01-26 05:39 |
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Articles in Press |
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2019-01-26 05:39 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-02-26 07:43 |
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Publish the Manuscript Online |
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2019-02-27 04:11 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Control Study |
| Article Title |
Triggers of histologically suspected drug-induced colitis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Thorsten Brechmann, Katharina Günther, Matthias Neid, Wolff Schmiegel and Andrea Tannapfel |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Thorsten Brechmann, MD, Doctor, Doctor, Senior Researcher, Department of Gastroenterology and Hepatology, Ruhr-University Bochum, Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil gGmbH, Bürkle-de-la-Camp-Platz 1, Bochum 44789, Germany. thorsten.brechmann@rub.de |
| Key Words |
Drug toxicity; Drug-induced colitis; Ischaemic colitis; Drug-associated gastrointestinal disease; Atherosclerosis; Colonic ischaemia; Nonsteroidal anti-inflammatory drugs; Fibrates |
| Core Tip |
Several drugs have been attributed to drug-induced colitis (DiC). In this systematical age- and gender-matched retrospective cohort study based on histopathological findings DiC was associated with drugs predominantly indicated for the treatment of cardiovascular and related diseases, nonsteroidal anti-inflammatory drugs, with atherosclerosis, particularly coronary heart disease, and hyperlipoproteinaemia. Histopathology was reassessed in three groups (DiC with atherosclerosis, DiC without atherosclerosis and ischaemic colitis each); both DiC groups presented milder inflammation than ischaemic colitis; DiC patients with atherosclerosis exhibited histological features from both other groups. In conclusion, atherosclerosis and microcirculatory disturbances seem to play an important pathogenetic role. |
| Publish Date |
2019-02-27 04:11 |
| Citation |
Brechmann T, Günther K, Neid M, Schmiegel W, Tannapfel A. Triggers of histologically suspected drug-induced colitis. World J Gastroenterol 2019; 25(8): 967-979 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i8/967.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i8.967 |
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