Publication Name	World Journal of Experimental Medicine
Manuscript ID	4365
Country	Greece

Received	2013-06-28 11:09
Peer-Review Started	2013-06-28 17:09
To Make the First Decision	2013-08-08 11:10
Return for Revision	2013-08-15 09:34
Revised	2013-09-06 16:39
Second Decision	2013-11-01 16:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-11-03 11:07
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-11-18 11:51
Publish the Manuscript Online	2013-11-20 17:44

ISSN	2220-315x (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Biochemistry & Molecular Biology
Manuscript Type	Review
Article Title	Mechanotransduction in bone: Intervening in health and disease
Manuscript Source	Invited Manuscript
All Author List	Anastasia Spyropoulou and Efthimia K Basdra
Funding Agency and Grant Number
Corresponding Author	Efthimia K Basdra, PhD, Associate Professor, Department of Biological Chemistry, Cellular and Molecular Biomechanics Unit, University of Athens Medical School, 75, M. Asias Street, GR-11527 Athens, Greece. tegk.84@gmail.com
Key Words	Mechanotransduction; Bone remodeling; Bone disease; Bone health
Core Tip	Mechanotransduction has been shown to be of major significance in modulating bone remodeling under physiological and pathological conditions. Therefore the study of the underlying mechanisms is of major importance and necessary step towards the better understanding of bone biology as well as the development of therapeutic strategies against conditions characterised by deregulated mechanotransduction. This review will consider the molecular mechanisms behind mechanotransduction as well as the scientific models currently used for its better understanding. It will also focus on mechanostimulatory techniques that could be used against a variety of deregulated mechanotransduction-related diseases.
Publish Date	2013-11-20 17:44
Citation	Spyropoulou A, Basdra EK. Mechanotransduction in bone: Intervening in health and disease. World J Exp Med 2013; 3(4): 74-86
URL	http://www.wjgnet.com/2220-315X/full/v3/i4/74.htm
DOI	http://dx.doi.org/10.5493/wjem.v3.i4.74

Full Article (PDF)	WJEM-3-74.pdf
Manuscript File	4365-Review.docx
Answering Reviewers	4365-Answering reviewers.pdf
Copyright License Agreement	4365-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	4365-Language certificate.PDF
Peer-review Report	4365-Peer review(s).pdf
Scientific Editor Work List	4365-Scientific editor work list.doc