Publication Name	World Journal of Biological Chemistry
Manuscript ID	4371
Country	United States

Received	2013-06-28 11:42
Peer-Review Started	2013-06-28 17:48
To Make the First Decision	2013-07-26 18:30
Return for Revision	2013-08-06 09:49
Revised	2013-08-31 02:53
Second Decision	2013-11-04 16:29
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-11-05 09:03
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-11-26 12:13
Publish the Manuscript Online	2013-12-06 18:20

ISSN	1949-8454 (online)
Open Access
Copyright
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Website	http://www.wjgnet.com

Category	Biochemistry & Molecular Biology
Manuscript Type	Minireviews
Article Title	Adaptive and maladaptive expression of the mRNA regulatory protein HuR
Manuscript Source	Invited Manuscript
All Author List	Suman Govindaraju and Beth S Lee
Funding Agency and Grant Number
Corresponding Author	Beth S Lee, PhD, Associate Professor, Department of Physiology and Cell Biology, Ohio State University College of Medicine, 304 Hamilton Hall, 1645 Neil Avenue, Columbus, OH 43210, United States. lee.2076@osu.edu
Key Words	HuR; RNA binding proteins; Transcription; RNA stability; Translation; Protein stability; Cell stress; MicroRNAs; Cancer
Core Tip	HuR is an RNA-binding protein that regulates post-transcriptional processing of thousands of mRNAs, including many that encode proteins that are critical to basic cellular functions. Thus, while loss of HuR can lead to cell death, pathological overexpression of HuR is associated with numerous types of cancer. However, the mechanisms that govern expression of HuR have only begun to be delineated. This review summarizes the current state of knowledge of these mechanisms and how they may contribute to cell survival and pathology.
Publish Date	2013-12-06 18:20
Citation	Govindaraju S, Lee BS. Adaptive and maladaptive expression of the mRNA regulatory protein HuR. World J Biol Chem 2013; 4(4): 111-118
URL	http://www.wjgnet.com/1949-8454/full/v4/i4/111.htm
DOI	http://dx.doi.org/10.4331/wjbc.v4.i4.111

Full Article (PDF)	WJBC-4-111.pdf
Manuscript File	4371-Review.docx
Answering Reviewers	4371-Answering reviewers.pdf
Copyright License Agreement	4371-Copyright assignment.pdf
Peer-review Report	4371-Peer reviewer(s).pdf
Scientific Editor Work List	4371-Scientific editor work list.doc