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Publication Name World Journal of Stem Cells
Manuscript ID 4383
Country South Africa
Received
2013-06-28 12:34
Peer-Review Started
2013-06-28 19:09
To Make the First Decision
2013-07-05 18:33
Return for Revision
2013-07-09 13:13
Revised
2013-07-13 12:01
Second Decision
2013-08-16 19:45
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-08-17 00:15
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2013-09-11 13:46
Publish the Manuscript Online
2013-10-31 14:50
ISSN 1948-0210 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cell Biology
Manuscript Type Review
Article Title MicroRNAs as novel regulators of stem cell fate
Manuscript Source Invited Manuscript
All Author List Eunhyun Choi, Eunmi Choi and Ki-Chul Hwang
Funding Agency and Grant Number
Funding Agency Grant Number
South Korea Science 2011-0019243
Engineering Foundation 2011-0019254
South Korea Health 21 R and D Project, Ministry of Health and Welfare, South Korea A120478
Korea Health 21 R and D Project, Ministry of Health and Welfare, South Korea A085136
Corresponding Author Ki-Chul Hwang, PhD, Severance Biomedical Science Institute, Cardiovascular Research Institute, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-752, South Korea. kchwang@yuhs.ac
Key Words MicroRNA; Stem cell fate; Differentiation; Self-renewal; Reprogramming; Small molecule
Core Tip Stem cells are important in regenerative medicine applications due to their capacity to self-renew and differentiate into specific cell types. MicroRNAs (miRNAs) are short non-coding RNAs that negatively regulate gene expression at the post-transcriptional level. Recent studies suggest that miRNAs are key molecules in the regulation of stem cell fate decisions; this regulation is manifested as the fine tuning of cell- and tissue-specific gene expression. This review summarizes the current insights into stem cell fate determination by miRNAs and focuses on stem cell self-renewal, differentiation, and reprogramming. Small molecules that control stem cell fate are also highlighted.
Publish Date 2013-10-31 14:50
Citation Choi E, Choi E, Hwang KC. MicroRNAs as novel regulators of stem cell fate. World J Stem Cells 2013; 5(4): 172-187
URL http://www.wjgnet.com/1948-0210/full/v5/i4/172.htm
DOI http://dx.doi.org/10.4252/wjsc.v5.i4.172
Full Article (PDF) WJSC-5-172.pdf
Manuscript File 4383-Review.docx
Answering Reviewers 4383-Answering Reviewers.pdf
Copyright License Agreement 4383-Copyright Assignment.pdf
Non-Native Speakers of English Editing Certificate 4383-Language certificate.pdf
Peer-review Report 4383-Peer review(s).pdf
Scientific Editor Work List 4383-Scientific editor work list.doc