Publication Name	World Journal of Gastroenterology
Manuscript ID	4405
Country	United Kingdom

Received	2013-06-29 09:26
Peer-Review Started	2013-06-29 22:48
To Make the First Decision	2013-07-19 08:36
Return for Revision	2013-07-20 21:19
Revised	2013-07-23 17:35
Second Decision	2013-09-16 17:33
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-09-17 06:21
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-11-18 11:40
Publish the Manuscript Online	2013-12-11 16:13

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Editorial
Article Title	Is liver biopsy necessary in the management of alcoholic hepatitis?
Manuscript Source	Invited Manuscript
All Author List	Ashwin D Dhanda, Peter L Collins and C Anne McCune
Funding Agency and Grant Number
Corresponding Author	C Anne McCune, FRCP, MD, Department of Liver Medicine, University Hospitals Bristol NHS Foundation Trust, Marlborough Street, Bristol BS2 8HW, United Kingdom. anne.mccune@uhbristol.nhs.uk
Key Words	Alcoholic hepatitis; Liver biopsy; Diagnosis; Prognosis; Transjugular liver biopsy
Core Tip	Acute alcoholic hepatitis (AAH) is a clinical syndrome of jaundice and coagulopathy in a patient with a recent history of heavy alcohol consumption. Clinical diagnosis is challenging and transjugular liver biopsy remains the gold standard. Here we discuss the literature which demonstrates there is a lack of agreement between clinical and histological diagnosis. This, together with limited availability of transjugular liver biopsy makes it impossible to advocate universal biopsy in all suspected cases of AAH. We suggest further research is conducted to prospectively compare histological and clinical parameters and to develop a reliable and accurate non-invasive diagnostic tool.
Publish Date	2013-12-11 16:13
Citation	Dhanda AD, Collins PL, McCune CA. Is liver biopsy necessary in the management of alcoholic hepatitis? World J Gastroenterol 2013; 19(44): 7825-7829
URL	http://www.wjgnet.com/1007-9327/full/v19/i44/7825.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i44.7825

Full Article (PDF)	WJG-19-7825.pdf
Manuscript File	4405-Review.docx
Answering Reviewers	4405-Answering reviewers.pdf
Copyright License Agreement	4405-Copyright assignment.pdf
Peer-review Report	4405-Peer reviewer(s).pdf
Scientific Editor Work List	4405-Scientific editor work list.doc