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Articles Published Processes
1/29/2019 2:00:23 AM | Browse: 869 | Download: 1630
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Received |
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2018-11-19 02:40 |
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Peer-Review Started |
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2018-11-19 06:57 |
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To Make the First Decision |
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2018-12-14 08:15 |
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Return for Revision |
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2018-12-19 04:20 |
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Revised |
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2018-12-21 09:33 |
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Second Decision |
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2018-12-29 05:07 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2018-12-30 02:31 |
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Articles in Press |
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2018-12-30 02:31 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-01-23 10:20 |
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Publish the Manuscript Online |
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2019-01-29 02:00 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Overexpression of HSP27 and HSP70 is associated with decreased survival among patients with esophageal adenocarcinoma
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Henna K Söderström, Juha T Kauppi, Niku Oksala, Timo Paavonen, Leena Krogerus, Jari Räsänen and Tuomo Rantanen |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Tuomo Rantanen, MD, PhD, Professor, Department of Surgery, Kuopio University Hospital, Box 100, Kuopio 70029, Finland. tuomo.rantanen@kuh.fi |
| Key Words |
Esophageal adenocarcinoma; Heat shock proteins; Heat shock protein 27; Heat shock protein 70; Overexpression; Survival |
| Core Tip |
Heat shock proteins (HSPs) are classified according to molecular weight into distinct protein families, and they are present in all human cells. Overexpression of HSPs is associated with several malignancies and contributes to the development, progression, and metastasis of cancer, in addition to the inhibition of cellular death. In recent years, there has been active research into using HSP inhibitors in several malignancies. Because of the poor prognosis of esophageal adenocarcinoma (EAC), it would be valuable to find new biomarkers for the development of cancer treatments. We conducted the present study to analyze the expression of HSP27 and HSP70, and their association with survival, in patients with EAC. |
| Publish Date |
2019-01-29 02:00 |
| Citation |
Söderström HK, Kauppi JT, Oksala N, Paavonen T, Krogerus L, Räsänen J, Rantanen T. Overexpression of HSP27 and HSP70 is associated with decreased survival among patients with esophageal adenocarcinoma. World J Clin Cases 2019; 7(3): 260-269 |
| URL |
https://www.wjgnet.com/2307-8960/full/v7/i3/260.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v7.i3.260 |
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