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Articles Published Processes
2/27/2019 4:11:15 AM | Browse: 1093 | Download: 1756
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Received |
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2018-12-04 01:16 |
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Peer-Review Started |
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2018-12-06 10:01 |
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To Make the First Decision |
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2019-01-07 03:04 |
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Return for Revision |
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2019-01-08 02:33 |
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Revised |
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2019-01-18 11:25 |
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Second Decision |
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2019-01-25 10:06 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-01-26 05:36 |
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Articles in Press |
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2019-01-26 05:36 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2019-01-30 01:56 |
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Typeset the Manuscript |
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2019-02-26 07:45 |
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Publish the Manuscript Online |
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2019-02-27 04:11 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Observational Study |
Article Title |
Lethal-7 related polymorphisms are associated with susceptibility to and prognosis of gastric cancer
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Zhi-Fang Jia, Dong-Hui Cao, Yan-Hua Wu, Mei-Shan Jin, Yu-Chen Pan, Xue-Yuan Cao and Jing Jiang |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Natural Science Foundation of China |
81703293 |
National Natural Science Foundation of China |
81673145 |
National Natural Science Foundation of China |
81373084 |
the Research Program of the Education Department of Jilin Province |
2016487 |
the Scientific and Technological Development Program of Jilin Province |
20180520117JH |
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Corresponding Author |
Jing Jiang, PhD, Professor, Statistician, Division of Clinical Research, the First Hospital of Jilin University, No 71 Xinmin street, Changchun 130021, Jilin Province, China. jiangjing19702000@jlu.edu.cn |
Key Words |
Gastric cancer; Risk; Susceptibility; Prognosis; Polymorphism; Lethal-7; LIN28A; IL23R |
Core Tip |
This study included a relatively large number of gastric cancer patients and tumor-free controls and explored the relationship of ten lethal-7 (let-7) related single nucleotide polymorphisms (SNPs) with gastric carcinogenesis and prognosis. The results showed that the LIN28A rs3811463 polymorphism of the let-7 target was associated with the development of gastric cancer and that the IL23R rs10889677 polymorphism was related to the overall survival of gastric cancer patients in a dose-dependent manner. This study adds evidence that polymorphisms represent a genetic factor that modifies the susceptibility to and prognosis of gastric cancer. |
Publish Date |
2019-02-27 04:11 |
Citation |
Jia ZF, Cao DH, Wu YH, Jin MS, Pan YC, Cao XY, Jiang J. Lethal-7-related polymorphisms are associated with susceptibility to and prognosis of gastric cancer. World J Gastroenterol 2019; 25(8): 1012-1023 |
URL |
https://www.wjgnet.com/1007-9327/full/v25/i8/1012.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v25.i8.1012 |
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