Publication Name	World Journal of Immunology
Manuscript ID	4489
Country	Greece

Received	2013-07-02 09:49
Peer-Review Started	2013-07-02 15:23
To Make the First Decision	2013-07-19 08:48
Return for Revision	2013-07-20 22:33
Revised	2013-07-29 22:00
Second Decision	2013-09-13 15:00
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-09-13 22:53
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-10-29 16:59
Publish the Manuscript Online	2013-11-29 02:07

ISSN	2219-2824 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Immunology
Manuscript Type	Minireviews
Article Title	Decoy receptor 3: Its role as biomarker for chronic inflammatory diseases
Manuscript Source	Invited Manuscript
All Author List	Spyros I Siakavellas and Giorgos Bamias
Funding Agency and Grant Number
Corresponding Author	Giorgos Bamias, MD, Academic Department of Gastroenterology, Ethnikon and Kapodistriakon University, Laikon Hospital, 17 Agiou Thoma Str., 11527 Athens, Greece. gbamias@gmail.com
Key Words	Decoy receptor 3; Tumor necrosis factor receptor superfamily of proteins; Chronic inflammation; Infection; Disease activity; Biomarker
Core Tip	Members of the tumor-necrosis factor-? (TNF-?) and TNF-? receptor superfamilies play important roles in the function of the immune system. Decoy receptor 3 (DcR3) is a decoy receptor that exists only as soluble protein and has the ability to bind to FasL, LIGHT and TL1A. Recent studies showed that DcR3 is upregulated and may be pathogenetically implicated in systemic lupus erythematosus, rheumatoid arthritis, inflammatory bowel disease and infection. DcR3 may become a useful biomarker for chronic inflammatory disorders, as it is upregulated in response to inflammatory stimuli, and may serve both as a prognostic factor for disease severity and as an indicator of response to treatment.
Publish Date	2013-11-29 02:07
Citation	Siakavellas SI, Bamias G. Decoy receptor 3: Its role as biomarker for chronic inflammatory diseases. World J Immunol 2013; 3(3): 44-53
URL	http://www.wjgnet.com/2219-2824/full/v3/i3/44.htm
DOI	http://dx.doi.org/10.5411/wji.v3.i3.44

Full Article (PDF)	WJI-3-44.pdf
Manuscript File	4489-Review.docx
Answering Reviewers	4489-Answering reviewers.pdf
Copyright License Agreement	4489-Copyright assignment.docx
Peer-review Report	4489-Peer reviewer(s).pdf
Scientific Editor Work List	4489-Scientific editor work list.doc