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Articles Published Processes
5/14/2019 7:58:39 AM | Browse: 1167 | Download: 1505
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Received |
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2019-02-02 05:45 |
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Peer-Review Started |
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2019-02-06 05:20 |
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To Make the First Decision |
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2019-02-14 01:10 |
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Return for Revision |
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2019-02-15 04:43 |
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Revised |
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2019-03-27 05:30 |
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Second Decision |
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2019-03-29 10:35 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-03-30 00:39 |
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Articles in Press |
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2019-03-30 00:39 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-05-14 00:32 |
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Publish the Manuscript Online |
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2019-05-14 07:58 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Harnessing the potential of gene editing technology using CRISPR in inflammatory bowel disease
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Viktor Limanskiy, Arpita Vyas, Lakshmi Shankar Chaturvedi and Dinesh Vyas |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Dinesh Vyas, MD, MSc, Associate Professor, Director, Director, Surgeon, Department of Surgery, San Joaquin General Hospital, 500 West Hospital Road, French Camp, CA 95231, United States. dineshvyas@yahoo.com |
| Key Words |
Clustered regularly interspersed short palindromic repeats; Inflammatory bowel disease; Crohn’s disease; Ulcerative colitis; Gene excision; Gene editing; Gene therapy; Financial impact of inflammatory bowel disease on healthcare; Clustered regularly interspersed short palindromic repeats crossfire |
| Core Tip |
Using clustered regularly interspaced short palindromic repeats/CRISPR associated protein 9 (CRISPR/Cas9) to harness the potential of gene editing technology implicated in inflammatory bowel disease. This revolutionary way of editing genes and its application of gene manipulation is only gaining momentum. Genes such as Gatm (Glycine amidinotransferase, mitochondrial) and nucleotide-binding oligomerization domain-containing protein 2 have been utilized to show CRISPR is able to manipulate these genes precisely, and this is just the beginning. |
| Publish Date |
2019-05-14 07:58 |
| Citation |
Limanskiy V, Vyas A, Chaturvedi LS, Vyas D. Harnessing the potential of gene editing technology using CRISPR in inflammatory bowel disease. World J Gastroenterol 2019; 25(18): 2177-2187 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i18/2177.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i18.2177 |
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