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Articles Published Processes
5/6/2019 10:43:10 AM | Browse: 994 | Download: 1633
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Received |
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2018-12-26 01:16 |
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Peer-Review Started |
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2018-12-27 07:54 |
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To Make the First Decision |
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2019-01-21 02:24 |
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Return for Revision |
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2019-01-27 03:41 |
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Revised |
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2019-02-23 09:07 |
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Second Decision |
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2019-03-15 08:59 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-03-16 22:48 |
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Articles in Press |
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2019-03-16 22:48 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-05-06 06:21 |
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Publish the Manuscript Online |
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2019-05-06 10:43 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Report |
| Article Title |
Sofosbuvir/Ribavirin therapy for patients experiencing failure of ombitasvir/paritaprevir/ritonavir + ribavirin therapy: Two cases report and review of literature
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ken Sato, Yuichi Yamazaki, Takeshi Kobayashi, Satoshi Takakusagi, Norio Horiguchi, Satoru Kakizaki, Masayasu Andou, Yoshihiro Matsuda, Toshio Uraoka, Hiroshi Ohnishi and Hiroaki Okamoto |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Ken Sato, MD, PhD, Assistant Professor, Department of Gastroenterology and Hepatology, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi 371-8511, Gunma, Japan. satoken@gunma-u.ac.jp |
| Key Words |
Direct-acting antiviral agent failure; Hepatitis C; Genotype 2; Ribavirin; Sofosbuvir; Case report |
| Core Tip |
The effectiveness of sofosbuvir/ribavirin (SOF/RBV) therapy was unknown for patients who experienced failure of ombitasvir/paritaprevir/ritonavir plus ribavirin therapy and had hepatitis C virus genotype 2. Although there were only 2 patients, SOF/RBV therapy was effective. However, both patients experienced adverse events including unanticipated development or deterioration of autoimmune diseases. Because SOF/RBV therapy is generally well-tolerated, one of the patients was considered a specific case. However, the cases suggest SOF/RBV therapy should be carefully applied in case of the existence of baseline autoimmune disease. Our case reports warrant future studies, but careful observation during and after treatment is required. |
| Publish Date |
2019-05-06 10:43 |
| Citation |
Sato K, Yamazaki Y, Kobayashi T, Satoshi Takakusagi S, Horiguchi N, Kakizaki S, Andou M, Matsuda Y, Uraoka T, Ohnishi H, Okamoto H. Sofosbuvir/Ribavirin therapy for patients experiencing failure of ombitasvir/paritaprevir/ritonavir + ribavirin therapy: Two cases report and review of literature. World J Clin Cases 2019; 7(9): 1043-1052 |
| URL |
https://www.wjgnet.com/2307-8960/full/v7/i9/1043.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v7.i9.1043 |
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