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Articles Published Processes
5/6/2019 10:43:10 AM | Browse: 611 | Download: 878
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Received |
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2018-12-25 01:09 |
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Peer-Review Started |
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2018-12-27 07:35 |
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To Make the First Decision |
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2019-02-11 00:31 |
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Return for Revision |
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2019-02-21 01:59 |
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Revised |
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2019-02-25 07:28 |
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Second Decision |
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2019-03-07 10:24 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2019-03-09 05:38 |
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Articles in Press |
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2019-03-09 05:38 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2019-04-09 01:11 |
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Typeset the Manuscript |
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2019-05-06 04:48 |
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Publish the Manuscript Online |
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2019-05-06 10:43 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Case Report |
| Article Title |
Crizotinib-induced acute fatal liver failure in an Asian ALK-positive lung adenocarcinoma patient with liver metastasis: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ying Zhang, Yan-Yan Xu, Yi Chen, Jin-Na Li and Ying Wang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Project of Science and Technology of Shenyang |
No. F13-318-1-69 |
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| Corresponding Author |
Ying Wang, MSc, Professor, Department of Oncology, Shengjing Hospital of China Medical University, 39 Huaxiang Street, Tiexi District, Shenyang 110022, Liaoning Province, China. wang_ying@sj-hospital.org |
| Key Words |
Fatal liver failure; Crizotinib hepatotoxicity; Liver metastases; ALK rearrangement; Lung adenocarcinoma; Case report |
| Core Tip |
Crizotinib-induce hepatotoxicity is rare and non-specific and severe hepatotoxicity could develop to fatal liver failure. We report a case of fatal liver failure induced by crizotinib in a 37-year-old Asian patient with ALK-rearranged lung adenocarcinoma combined with hepatic metastasis. Physicians should be aware of the potential fatal adverse effect of crizotinib. The King’s College Criteria and liver enzymes weekly monitoring are necessary to the diagnosis and evaluation of crizotinib-induced liver failure. |
| Publish Date |
2019-05-06 10:43 |
| Citation |
Zhang Y, Xu YY, Chen Y, Li JN, Wang Y. Crizotinib-induced acute fatal liver failure in an Asian ALK-positive lung adenocarcinoma patient with liver metastasis: A case report. World J Clin Cases 2019; 7(9): 1080-1086 |
| URL |
https://www.wjgnet.com/2307-8960/full/v7/i9/1080.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v7.i9.1080 |
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