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4/29/2019 4:13:18 AM | Browse: 884 | Download: 1117
Publication Name World Journal of Cardiology
Manuscript ID 45336
Country/Territory United States
Received
2019-01-08 03:35
Peer-Review Started
2019-01-08 07:54
To Make the First Decision
2019-01-22 02:29
Return for Revision
2019-01-28 00:57
Revised
2019-03-19 00:52
Second Decision
2019-03-19 09:56
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-03-28 04:14
Articles in Press
2019-03-28 04:14
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-04-29 01:42
Publish the Manuscript Online
2019-04-29 04:13
ISSN 1949-8462 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cardiac & Cardiovascular Systems
Manuscript Type Meta-Analysis
Article Title Who benefits from percutaneous closure of patent foramen ovale vs medical therapy for stroke prevention? In-depth and updated meta-analysis of randomized trials
Manuscript Source Invited Manuscript
All Author List Khagendra Dahal, Adil Yousuf, Hussam Watti, Brannen Liang, Sharan Sharma, Jharendra Rijal, Pavan Katikaneni, Kalgi Modi, Neeraj Tandon, Michael Azrin and Juyong Lee
ORCID
Author(s) ORCID Number
Khagendra Dahal http://orcid.org/0000-0001-53350846
Adil Yousuf http://orcid.org/0000-0002-9849-0938
Hussam Watti http://orcid.org/0000-0002-4243-1431
Brannen Liang http://orcid.org/0000-0002-6384-5938
Sharan Sharma http://orcid.org/0000-0003-1475-6004
Jharendra Rijal http://orcid.org/0000-0002-6964-8513
Kalgi Modi http://orcid.org/0000-0001-8651-0826
Neeraj Tandon http://orcid.org/0000-0002-8108-698X
Michael Azrin http://orcid.org/0000-0002-2669-0703
Juyong Lee http://orcid.org/0000-0001-5412-5472
Funding Agency and Grant Number
Corresponding Author Juyong Lee, MD, PhD, Division of Cardiology, University of Connecticut Health Center, Farmington, CT 06030, United States. jlee@uchc.edu
Key Words Patent foramen ovale; Stroke; Antiplatelet therapy; Anticoagulation; Meta-analysis
Core Tip Closure of patent foramen ovale closure (PFOC) is a treatment modality for patients with stroke. To evaluate the efficacy and safety of PFOC vs medical therapy in different groups of patients presenting with stroke, we performed this meta-analysis of randomized trials following standard techniques. It showed that PFOC, compared to medical therapy reduced the risk of ischemic stroke and the composite outcome of stroke, transient ischemic attack (TIA) and systemic thromboembolism but no difference was observed in the risk of TIA, mortality and major bleeding. PFOC increased the risk of atrial fibrillation. Subgroup analyses showed that PFOC reduced the risk of stroke in males.
Publish Date 2019-04-29 04:13
Citation Dahal K, Yousuf A, Watti H, Liang B, Sharma S, Rijal J, Katikaneni P, Modi K, Tandon N, Azrin M, Lee J. Who benefits from percutaneous closure of patent foramen ovale vs medical therapy for stroke prevention? In-depth and updated meta-analysis of randomized trials. World J Cardiol 2019; 11(4): 126-136
URL URL: https://www.wjgnet.com/1949-8462/full/v11/i4/126.htm
DOI DOI: https://dx.doi.org/10.4330/wjc.v11.i4.126
Full Article (PDF) WJC-11-126.pdf
Full Article (Word) WJC-11-126.docx
Manuscript File 45336-Review.docx
Answering Reviewers 45336-Answering reviewers.pdf
Audio Core Tip 45336-Audio core tip.m4a
Biostatistics Review Certificate 45336-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 45336-Conflict-of-interest statement.pdf
Copyright License Agreement 45336-Copyright license agreement.pdf
Peer-review Report 45336-Peer-review(s).pdf
Scientific Misconduct Check 45336-Scientific misconduct check.pdf
Scientific Editor Work List 45336-Scientific editor work list.pdf