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Articles Published Processes
4/18/2019 10:30:43 AM | Browse: 1146 | Download: 1566
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Received |
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2019-01-02 06:14 |
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Peer-Review Started |
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2019-01-04 05:25 |
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To Make the First Decision |
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2019-01-30 00:00 |
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Return for Revision |
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2019-02-14 02:01 |
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Revised |
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2019-02-15 16:31 |
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Second Decision |
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2019-03-15 08:11 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-03-16 15:43 |
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Articles in Press |
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2019-03-16 15:43 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-04-18 02:18 |
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Publish the Manuscript Online |
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2019-04-18 10:30 |
| ISSN |
2218-5836 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Orthopedics |
| Manuscript Type |
Systematic Reviews |
| Article Title |
Growing pains: What do we know about etiology? A systematic review
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Vito Pavone, Andrea Vescio, Fabiana Valenti, Marco Sapienza, Giuseppe Sessa and Gianluca Testa |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Vito Pavone, MD, PhD, Associate Professor, Department of General Surgery and Medical Surgical Specialties, Section of Orthopaedics and Traumatology, University Hospital Policlinico-Vittorio Emanuele, University of Catania, Via Santa Sofia, 78, Catania 95123, Italy. vpavone@unict.it |
| Key Words |
Growing pains; Benign nocturnal limb pains of childhood; Recurrent limb pains of childhood; Etiology; Pathogenesis |
| Core Tip |
Growing pains are benign nocturnal limb pains and the most common cause of musculoskeletal pain in early childhood. Intermittent non-articular pain during the late afternoon or the night with intervals of pain-free days and no objective signs of inflammation are the main clinical features. Despite the etiology of the disease has been widely researched, it is still not fully understood. Lower pain threshold, vascular perfusion changes, anatomical and genetic abnormalities, vitamin D deficiency and psychological factors have been proposed to explain the pathogenesis of growing pain. More studies are needed to understand the complex genesis of the disease. |
| Publish Date |
2019-04-18 10:30 |
| Citation |
Pavone V, Vescio A, Valenti F, Sapienza M, Sessa G, Testa G. Growing pains: What do we know about etiology? A systematic review. World J Orthop 2019; 10(4): 192-205 |
| URL |
https://www.wjgnet.com/2218-5836/full/v10/i4/192.htm |
| DOI |
https://dx.doi.org/10.5312/wjo.v10.i4.192 |
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