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3/27/2019 10:37:20 AM | Browse: 1025 | Download: 1782
Publication Name World Journal of Hepatology
Manuscript ID 45667
Country/Territory Sweden
Received
2019-01-13 07:13
Peer-Review Started
2019-01-14 06:29
To Make the First Decision
2019-02-15 02:03
Return for Revision
2019-02-22 11:33
Revised
2019-02-27 16:21
Second Decision
2019-03-15 09:47
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-03-16 14:49
Articles in Press
2019-03-16 14:49
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-03-27 05:34
Publish the Manuscript Online
2019-03-27 10:37
ISSN 1948-5182 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Letter to the Editor
Article Title Persistent elevation of fibrosis biomarker cartilage oligomeric matrix protein following hepatitis C virus eradication
Manuscript Source Unsolicited Manuscript
All Author List Kristofer Andréasson, Göran Jönsson, Roger Hesselstrand and Hans Norrgren
ORCID
Author(s) ORCID Number
Kristofer Andréasson http://orcid.org/0000-0001-7021-2541
Göran Jönsson http://orcid.org/0000-0002-4436-7977
Roger Hesselstrand http://orcid.org/0000-0001-6794-2201
Hans Norrgren http://orcid.org/0000-0001-5780-530X
Funding Agency and Grant Number
Funding Agency Grant Number
Bengt Ihre Foundation SLS-594-301
Bengt Ihre Foundation SLS-789091
Corresponding Author Kristofer Andréasson, MD, PhD, Reader (Associate Professor), Section of Rheumatology, Department of Clinical Sciences Lund, Lund University, Kioskgatan 3, Lund S-221 85, Sweden. kristofer.andreasson@med.lu.se
Key Words Hepatitis C; Chronic; Cartilage oligomeric matrix protein; Fibrosis
Core Tip Cartilage oligomeric matrix protein (COMP) is a biomarker of fibrosis that has recently been introduced in the field of hepatology. COMP has also been associated with tumor development. This is the first prospective study of COMP in chronic liver disease. We confirm previous findings, relating S-COMP to liver cirrhosis. Eradication of hepatitis C was associated with improvements of liver function test and liver elasticity. In contrast, and unexpectedly, S-COMP remained unchanged in this cohort. We argue that the biomarker potential of COMP in chronic liver diseases needs further exploration, especially in reference to carcinoma development.
Publish Date 2019-03-27 10:37
Citation Andréasson K, Jönsson G, Hesselstrand R, Norrgren H. Persistent elevation of fibrosis biomarker cartilage oligomeric matrix protein following hepatitis C virus eradication. World J Hepatol 2019; 11(3): 330-334
URL https://www.wjgnet.com/1948-5182/full/v11/i3/330.htm
DOI https://dx.doi.org/10.4254/wjh.v11.i3.330
Full Article (PDF) WJH-11-330.pdf
Full Article (Word) WJH-11-330.docx
Manuscript File 45667-Review.docx
Answering Reviewers 45667-Answering reviewers.pdf
Audio Core Tip 45667-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 45667-Conflict-of-interest statement.pdf
Copyright License Agreement 45667-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 45667-Grant application form(s).pdf
Peer-review Report 45667-Peer-review(s).pdf
Scientific Misconduct Check 45667-Scientific misconduct check.pdf
Scientific Editor Work List 45667-Scientific editor work list.pdf