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Articles Published Processes
9/12/2019 10:38:02 AM | Browse: 984 | Download: 1511
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Received |
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2019-03-15 03:09 |
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Peer-Review Started |
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2019-03-18 00:19 |
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To Make the First Decision |
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2019-06-05 06:34 |
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Return for Revision |
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2019-06-06 03:45 |
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Revised |
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2019-07-05 05:51 |
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Second Decision |
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2019-08-16 08:03 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-08-19 03:14 |
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Articles in Press |
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2019-08-19 03:14 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-09-08 03:49 |
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Publish the Manuscript Online |
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2019-09-12 10:38 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019 Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Review |
| Article Title |
Tumor progression-dependent angiogenesis in gastric cancer and its potential application
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Ming-Ming Tsai and Hsi-Lung Hsieh |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Ming-Ming Tsai, PhD, Associate Professor, Department of Nursing, Division of Basic Medical Sciences,, Chang-Gung University of Science and Technology, 261 Wen-hwa 1 Road, Taoyuan 333, Taiwan. mmtsai@mail.cgust.edu.tw |
| Key Words |
Gastric cancer; Angiogenesis; Vascular endothelial cell; Angiogenic phenotype switch; Anti-angiogenesis; Tumor dormancy |
| Core Tip |
Tumor angiogenesis in GC and anti-angiogenic therapies for GC, including information from their preclinical to clinical trials and/or application, are discussed. The anti-angiogenic strategies include decreasing the expression of pro-angiogenic ligands and their receptors, increasing the level of angiogenic inhibitors, the direct targeting of the inner walls of ECs, and the administration of cell-cell adhesion inhibitors for advanced GC. This review provides a brief description of various tumor angiogenic factors for the purposes of diagnosis, prognosis and therapeutics and describes the anti-angiogenic drugs that are currently being investigated in preclinical and clinical trials. Hopefully, based on the molecular mechanism of tumor angiogenesis, we highlight the accuracy of diagnosis and prognosis and the selection of the most appropriate therapy for GC patients. |
| Publish Date |
2019-09-12 10:38 |
| Citation |
Hsieh HL, Tsai MM. Tumor progression-dependent angiogenesis in gastric cancer and its potential application. World J Gastrointest Oncol 2019; 11(9): 686-704 |
| URL |
https://www.wjgnet.com/1948-5204/full/v11/i9/686.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v11.i9.686 |
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