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Articles Published Processes
3/27/2019 10:37:20 AM | Browse: 959 | Download: 1305
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Received |
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2019-02-06 03:24 |
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Peer-Review Started |
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2019-02-06 14:01 |
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To Make the First Decision |
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2019-02-26 03:02 |
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Return for Revision |
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2019-03-05 00:33 |
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Revised |
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2019-03-06 14:30 |
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Second Decision |
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2019-03-15 10:09 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2019-03-16 14:53 |
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Articles in Press |
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2019-03-16 14:53 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-03-26 10:54 |
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Publish the Manuscript Online |
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2019-03-27 10:37 |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Minireviews |
Article Title |
Hepatocellular carcinoma recurrence after liver transplantation: Risk factors, screening and clinical presentation
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Manuscript Source |
Invited Manuscript |
All Author List |
Norma Arteiro Filgueira |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Norma Arteiro Filgueira, PhD, Professor, Department of Internal Medicine, Universidade Federal de Pernambuco, Av Beira Rio 591, apt 501, Recife 50610-100, Pernambuco, Brazil. norma.arteiro@hotmail.com |
Key Words |
Hepatocellular carcinoma; Liver transplantation; Recurrence; Risk factors; Alpha-fetoprotein; Survival; Prognosis |
Core Tip |
Recurrence of hepatocellular carcinoma (HCC) after liver transplantation usually portends a poor prognosis with short survival. Besides well recognized risk factors for post-transplant HCC recurrence, as tumor staging and vascular invasion, this review discusses other factors strongly associated with the recurrence risk, such as alpha-fetoprotein levels, tumor uptake of FDG in Pet scan, response to locoregional therapy and post-transplant immunosuppression. We present proposals of a screening protocol for tumor recurrence after transplantation and of criteria to identify patients with good prognosis after recurrence, who might benefit from aggressive antitumor therapy. |
Publish Date |
2019-03-27 10:37 |
Citation |
Filgueira NA. Hepatocellular carcinoma recurrence after liver transplantation: Risk factors, screening and clinical presentation. World J Hepatol 2019; 11(3): 261-272 |
URL |
https://www.wjgnet.com/1948-5182/full/v11/i3/261.htm |
DOI |
https://dx.doi.org/10.4254/wjh.v11.i3.261 |
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