Publication Name	World Journal of Hepatology
Manuscript ID	46289
Country	Brazil

Received	2019-02-06 03:24
Peer-Review Started	2019-02-06 14:01
First Decision by Editorial Office Director	2019-02-21 02:04
Return for Revision	2019-03-05 00:33
Revised	2019-03-06 14:30
Publication Fee Transferred
Second Decision by Editor	2019-03-15 10:09
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2019-03-16 14:53
Articles in Press	2019-03-16 14:53
Edit the Manuscript by Language Editor
Typeset the Manuscript	2019-03-26 10:54
Publish the Manuscript Online	2019-03-27 10:37

ISSN	1948-5182 (online)
Open Access
Copyright	© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Hepatocellular carcinoma recurrence after liver transplantation: Risk factors, screening and clinical presentation
Manuscript Source	Invited Manuscript
All Author List	Norma Arteiro Filgueira
ORCID	Author(s) ORCID Number Norma Arteiro Filgueira http://orcid.org/0000-0002-7549-9825
Funding Agency and Grant Number
Corresponding Author	Norma Arteiro Filgueira, PhD, Professor, Department of Internal Medicine, Universidade Federal de Pernambuco, Av Beira Rio 591, apt 501, Recife 50610-100, Pernambuco, Brazil. norma.arteiro@hotmail.com
Key Words	Hepatocellular carcinoma; Liver transplantation; Recurrence; Risk factors; Alpha-fetoprotein; Survival; Prognosis
Core Tip	Recurrence of hepatocellular carcinoma (HCC) after liver transplantation usually portends a poor prognosis with short survival. Besides well recognized risk factors for post-transplant HCC recurrence, as tumor staging and vascular invasion, this review discusses other factors strongly associated with the recurrence risk, such as alpha-fetoprotein levels, tumor uptake of FDG in Pet scan, response to locoregional therapy and post-transplant immunosuppression. We present proposals of a screening protocol for tumor recurrence after transplantation and of criteria to identify patients with good prognosis after recurrence, who might benefit from aggressive antitumor therapy.
Publish Date	2019-03-27 10:37
Citation	Filgueira NA. Hepatocellular carcinoma recurrence after liver transplantation: Risk factors, screening and clinical presentation. World J Hepatol 2019; 11(3): 261-272
URL	https://www.wjgnet.com/1948-5182/full/v11/i3/261.htm
DOI	https://dx.doi.org/10.4254/wjh.v11.i3.261

Full Article (PDF)	WJH-11-261.pdf
Full Article (Word)	WJH-11-261.docx
Manuscript File	46289-Review.docx
Answering Reviewers	46289-Answering reviewers.pdf
Audio Core Tip	46289-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	46289-Conflict-of-interest statement.pdf
Copyright License Agreement	46289-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	46289-Language certificate.pdf
Peer-review Report	46289-Peer-review(s).pdf
Scientific Misconduct Check	46289-Scientific misconduct check.pdf
Scientific Editor Work List	46289-Scientific editor work list.pdf
CrossCheck Report	46289-CrossCheck Report.pdf