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Articles Published Processes
10/16/2019 12:17:24 PM | Browse: 691 | Download: 881
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Received |
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2019-02-27 03:29 |
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Peer-Review Started |
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2019-02-27 12:12 |
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To Make the First Decision |
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2019-04-12 00:45 |
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Return for Revision |
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2019-04-24 07:16 |
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Revised |
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2019-05-01 13:00 |
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Second Decision |
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2019-09-12 09:56 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-09-12 17:07 |
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Articles in Press |
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2019-09-12 17:07 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-10-12 11:32 |
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Publish the Manuscript Online |
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2019-10-16 12:17 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Retrospective review of total neoadjuvant therapy
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Laila Babar, Veli Bakalov, Stephen Abel, Obaid Ashraf, Gene Grant Finley, Moses S Raj, Kristina Lundeen, Dulabh K Monga, Alexander V Kirichenko and Rodney E Wegner |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Laila Babar, MD, Doctor, Doctor, Department of Internal Medicine, Allegheny General Hospital, 320 E North Ave, Pittsburgh, PA 15212, United States. laila.babar@ahn.org |
| Key Words |
Total neoadjuvant therapy; Neoadjuvant chemoradiation; Multi-agent chemotherapy; Locally advanced rectal cancer; National cancer database; Colorectal cancer |
| Core Tip |
Total neoadjuvant treatment (TNT) has been gaining favor as the treatment of choice for rectal carcinoma. It has been linked to better sphincter preservation and overall improved quality of life. Our study aim was to compare TNT with traditional chemotherapy and radiation over the last 10 years and evaluate for differences in outcome. Our study confirms a rising trend in the of use of TNT especially in patients diagnosed with locally advanced rectal cancer. Patients treated with TNT had higher burden of disease and despite this, they had similar survival outcomes as those treated with traditional chemotherapy and radiation. |
| Publish Date |
2019-10-16 12:17 |
| Citation |
Babar L, Bakalov V, Abel S, Ashraf O, Finley GG, Raj MS, Lundeen K, Monga DK, Kirichenko AV, Wegner RE. Retrospective review of total neoadjuvant therapy. World J Gastrointest Oncol 2019; 11(10): 857-865 |
| URL |
https://www.wjgnet.com/1948-5204/full/v11/i10/857.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v11.i10.857 |
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