Publication Name	World Journal of Stem Cells
Manuscript ID	46496
Country	China

Received	2019-02-15 01:42
Peer-Review Started	2019-02-15 03:25
To Make the First Decision	2019-04-16 07:29
Return for Revision	2019-05-09 03:39
Revised	2019-05-12 13:23
Second Decision	2019-07-23 06:31
Accepted by Journal Editor-in-Chief	2019-07-23 18:32
Accepted by Executive Editor-in-Chief	2019-08-27 21:55
Articles in Press	2019-08-27 21:55
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2019-09-11 09:10
Publish the Manuscript Online	2019-09-25 03:03

ISSN	1948-0210 (online)
Open Access	This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Cell Biology
Manuscript Type	Review
Article Title	Induction of differentiation of human stem cells ex vivo: Toward large-scale platelet production
Manuscript Source	Invited Manuscript
All Author List	Xiao-Hua Lei, Yi-Qing Yang, Chi-Yuan Ma and En-Kui Duan
ORCID	Author(s) ORCID Number Xiao-Hua Lei http://orcid.org/0000-0001-8095-9008 Yi-Qing Yang http://orcid.org/0000-0001-8538-6042 Chi-Yuan Ma http://orcid.org/0000-0002-9054-644X En-Kui Duan http://orcid.org/0000-0002-2721-635X
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China Grants 31600683 National Natural Science Foundation of China Grants U1738103 Strategic Priority Research Program of the Chinese Academy of Sciences XDA15014000
Corresponding Author	Xiao-Hua Lei, PhD, Assistant Professor, State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, 1 Beichen West Road, Beijing 100101, China. leixh@ioz.ac.cn
Key Words	Megakaryopoiesis; Platelet production; Transfusion; Bioreactors; Stem cells;
Core Tip	Platelets derived from voluntary blood donation pose some challenges, such as susceptibility to pathogen contamination, short preservation time and difficulty in satisfying the increasing number of patients requiring platelet transfusion. Thus, seeking a safe and reliable alternative source of platelets is an effective solution.
Publish Date	2019-09-25 03:03
Citation	Lei XH, Yang YQ, Ma CY, Duan EK. Induction of differentiation of human stem cells ex vivo: Toward large-scale platelet production. World J Stem Cell 2019; 11(9):666-676
URL	https://www.wjgnet.com/1948-0210/full/v11/i9/666.htm
DOI	https://dx.doi.org/10.4252/wjsc.v11.i9.666

Full Article (PDF)	WJSC-11-666.pdf
Full Article (Word)	WJSC-11-666.docx
Manuscript File	46496-Review.docx
Answering Reviewers	46496-Answering reviewers.pdf
Audio Core Tip	46496-Audio core tip.WAV
Conflict-of-Interest Disclosure Form	46496-Conflict-of-interest statement.pdf
Copyright License Agreement	46496-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	46496-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	46496-Language certificate.pdf
Peer-review Report	46496-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	46496-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	46496-Scientific misconduct check.pdf
Scientific Editor Work List	46496-Scientific editor work list.pdf
CrossCheck Report	46496-CrossCheck report.pdf