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9/25/2019 3:03:24 AM | Browse: 1180 | Download: 2254
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Received |
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2019-02-25 03:12 |
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Peer-Review Started |
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2019-02-27 11:20 |
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First Decision by Editorial Office Director |
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2019-04-11 18:36 |
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Return for Revision |
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2019-04-19 09:54 |
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Revised |
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2019-07-26 07:08 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2019-08-07 00:45 |
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Second Decision by Editor-in-Chief |
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2019-08-07 22:58 |
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Final Decision by Editorial Office Director |
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2019-08-21 04:14 |
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Articles in Press |
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2019-08-21 04:14 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-09-17 12:04 |
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Publish the Manuscript Online |
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2019-09-25 03:03 |
| ISSN |
1948-0210 (online) |
| Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Neurosciences |
| Manuscript Type |
Review |
| Article Title |
Using induced pluripotent stem cells for modeling Parkinson’s disease
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Min-Jing Ke, Cheong-Meng Chong and Huan-Xing Su |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Huan-Xing Su, MD, PhD, Associate Professor, State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, University Northern Road, Macao 999078, China. huanxingsu@umac.mo |
| Key Words |
Parkinson's disease; Dopaminergic neurons; Induced pluripotent stem cells; Somatic cell reprogramming; Aging; |
| Core Tip |
Human induced pluripotent stem cell (iPSC)-derived dopaminergic neurons hold great promise for studying disease mechanisms underlying Parkinson’s disease (PD) and testing drug effects. A number of reviews have previously summarized the potential use of patient iPSCs for modeling PD. However, few of them comprehensively discuss the establishment of gene-editing-based iPSCs for PD and their application in research. Our objective is to consolidate the current literature on various iPSC-based PD models either derived from PD patients through reprogramming technology or established by gene-editing technology, and provide new insights into the application of iPSC PD models. |
| Publish Date |
2019-09-25 03:03 |
| Citation |
Ke MJ, Chong CM, Su HX. Using induced pluripotent stem cells for modeling Parkinson’s disease. World J Stem Cells 2019; 11(9):634-649 |
| URL |
https://www.wjgnet.com/1948-0210/full/v11/i9/634.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v11.i9.634 |
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