Publication Name	World Journal of Stem Cells
Manuscript ID	46595
Country	China

Received	2019-02-25 03:12
Peer-Review Started	2019-02-27 11:20
To Make the First Decision	2019-04-12 00:29
Return for Revision	2019-04-19 09:54
Revised	2019-07-26 07:08
Second Decision	2019-08-07 00:45
Accepted by Journal Editor-in-Chief	2019-08-07 22:58
Accepted by Company Editor-in-Chief	2019-08-21 04:14
Articles in Press	2019-08-21 04:14
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2019-09-17 12:04
Publish the Manuscript Online	2019-09-25 03:03

ISSN	1948-0210 (online)
Open Access	This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Neurosciences
Manuscript Type	Review
Article Title	Using induced pluripotent stem cells for modeling Parkinson’s disease
Manuscript Source	Invited Manuscript
All Author List	Min-Jing Ke, Cheong-Meng Chong and Huan-Xing Su
ORCID	Author(s) ORCID Number Min-Jing Ke http://orcid.org/0000-0003-4728-6918 Cheong-Meng Chong http://orcid.org/0000-0002-2462-4729 Huan-Xing Su http://orcid.org/0000-0003-3254-825X
Funding Agency and Grant Number
Corresponding Author	Huan-Xing Su, MD, PhD, Associate Professor, State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, University Northern Road, Macao 999078, China. huanxingsu@umac.mo
Key Words	Parkinson's disease; Dopaminergic neurons; Induced pluripotent stem cells; Somatic cell reprogramming; Aging;
Core Tip	Human induced pluripotent stem cell (iPSC)-derived dopaminergic neurons hold great promise for studying disease mechanisms underlying Parkinson’s disease (PD) and testing drug effects. A number of reviews have previously summarized the potential use of patient iPSCs for modeling PD. However, few of them comprehensively discuss the establishment of gene-editing-based iPSCs for PD and their application in research. Our objective is to consolidate the current literature on various iPSC-based PD models either derived from PD patients through reprogramming technology or established by gene-editing technology, and provide new insights into the application of iPSC PD models.
Publish Date	2019-09-25 03:03
Citation	Ke MJ, Chong CM, Su HX. Using induced pluripotent stem cells for modeling Parkinson’s disease. World J Stem Cells 2019; 11(9):634-649
URL	https://www.wjgnet.com/1948-0210/full/v11/i9/634.htm
DOI	https://dx.doi.org/10.4252/wjsc.v11.i9.634

Full Article (PDF)	WJSC-11-634.pdf
Full Article (Word)	WJSC-11-634.docx
Manuscript File	46595-Review.doc
Answering Reviewers	46595-Answering reviewers.pdf
Audio Core Tip	46595-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	46595-Conflict-of-interest statement.pdf
Copyright License Agreement	46595-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	46595-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	46595-Language certificate.pdf
Peer-review Report	46595-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	46595-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	46595-Scientific misconduct check.pdf
Scientific Editor Work List	46595-Scientific editor work list.pdf